Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 7/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | FABP2 | P12104 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837748 | 0.86 | MAPT (0.49) | GRIA4NPSR1PTGS1MEN1PTGS2 | |
| SCHEMBL11728161 | 0.86 | GRIA4 (0.50) | GRIA4NPSR1PTGS1MEN1PTGS2 | |
| SCHEMBL10705388 | 0.85 | MAOB (0.53) | GRIA4NPSR1PTGS1PGRPDE4A | |
| SCHEMBL11849305 | 0.84 | GRIA4 (0.46) | GRIA4NPSR1PTGS1PGRPDE4A | |
| Hydrochloric Acid SCHEMBL27850093 | 0.84 | MAOB (0.52) | GRIA4NPSR1PTGS1PGRPDE4A | |
| SCHEMBL27915165 | 0.84 | TSHR (0.43) | PTGS2TSHRLMNAHPGDALDH1A1 | |
| SCHEMBL8755060 | 0.83 | PTGS2 (0.70) | NPSR1PTGS1PGRPDE4AMEN1 | |
| SCHEMBL17918662 | 0.83 | PTGS2 (0.70) | NPSR1PTGS1PGRPDE4AMEN1 | |
| SCHEMBL31456322 | 0.83 | PTGS2 (0.70) | NPSR1PTGS1PGRPDE4AMEN1 | |
| SCHEMBL9555720 | 0.83 | PTGS2 (0.70) | NPSR1PTGS1PGRPDE4AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979226-B1 | ISOXAZOLE DERIVATIVES | SUMITOMO PHARMA (JP) | 2005-11-09 | — | — | EP | disclosed |
| US-6100260-A | ((3-(1-(2-FLUORO-BIPHENYL-4-YL)-ETHYL)-ISOXAZOL-5-YLIMINO) -MORPHOLIN-4-YL-M ETHYL)-AMINE, FOR EXAMPLE; ADMINISTERING TO TREAT AUTOIMMUNE DISEASES AND INFLAMMATION | SUMITOMO PHARMACEUTICAL COMPANY, LIMITED (JP) | 2000-08-08 | — | — | US | disclosed |