Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 5/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13051720 | 0.79 | CYP3A4 (0.40) | KDM4EALDH1A1LMNAMEN1HPGD | |
| SCHEMBL19640087 | 0.75 | ERN1 (0.50) | KDM4ELMNAACHEERN1SHBG | |
| SCHEMBL25732294 | 0.74 | S1PR4 (0.35) | KDM4EALDH1A1LMNAACHESHBG | |
| SCHEMBL516188 | 0.73 | CYP3A4 (0.46) | KDM4EALDH1A1LMNAMEN1HPGD | |
| SCHEMBL19985855 | 0.73 | ACHE (0.37) | KDM4EALDH1A1LMNAMEN1HPGD | |
| SCHEMBL4420463 | 0.73 | ALDH1A1 (0.44) | KDM4EALDH1A1LMNAMEN1HPGD | |
| SCHEMBL30216932 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TRIM24TRIM33ERN1NPC1 | |
| SCHEMBL13177068 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TRIM24TRIM33ERN1NPC1 | |
| SCHEMBL11851066 | 0.72 | ERN1 (0.50) | KDM4EALDH1A1LMNAHPGDAOX1 | |
| SCHEMBL3274358 | 0.72 | MEN1 (0.43) | KDM4EALDH1A1LMNAMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103957-B1 | SUBSTITUTED BENZYL ESTERS, INTERMEDIATES THEREFOR, PROCESSES FOR THEIR PREPARATION AND THE USE OF THE ESTERS AS PESTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-04-20 | — | — | EP | disclosed |
| US-4515808-A | INSECTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-05-07 | — | — | US | disclosed |
| EP-0103957-A2 | Substituted benzyl esters, intermediates therefor, processes for their preparation and the use of the esters as pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-03-28 | — | — | EP | disclosed |