SCHEMBL10705446

SCHEMBL10705446

CCCCOC1=C(Cl)C(=O)c2ccccc2C1=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.55
NSD2 O96028 3/20 0.50
HSP90AA1 P07900 2/20 0.50
HKDC1 Q2TB90 2/20 0.50
TLR9 Q9NR96 2/20 0.50
IDO1 P14902 1/20 0.50
DNMT1 P26358 1/20 0.50
DNMT3L Q9UJW3 1/20 0.50
DNMT3A Q9Y6K1 1/20 0.50
MAPT P10636 8/20 0.48
TDP1 Q9NUW8 4/20 0.48
MAPK1 P28482 3/20 0.48
NPSR1 Q6W5P4 3/20 0.48
KDM4E B2RXH2 3/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
ALDH1A1 P00352 4/20 0.47
LMNA P02545 3/20 0.47
POLB P06746 2/20 0.47
MITF O75030 2/20 0.47
USP2 O75604 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10707493 0.95 PTPN1 (0.61) PTPN1NSD2HSP90AA1HKDC1TLR9
SCHEMBL10446464 0.87 IDO1 (0.56) PTPN1NSD2HSP90AA1HKDC1TLR9
SCHEMBL10863317 0.87 MAPT (0.44) PTPN1NSD2HSP90AA1HKDC1TLR9
SCHEMBL9643214 0.87 PTPN1 (0.58) PTPN1NSD2MAPTTDP1MAPK1
Benzene SCHEMBL9714013 0.86 NSD2 (0.58) PTPN1NSD2HSP90AA1HKDC1TLR9
SCHEMBL9627500 0.82 CDC25B (0.55) PTPN1MAPTTDP1KDM4EALDH1A1
SCHEMBL10446166 0.81 IDO1 (0.52) PTPN1NSD2HSP90AA1HKDC1TLR9
SCHEMBL9627657 0.81 PTPN1 (0.53) PTPN1NSD2MAPTTDP1MAPK1
SCHEMBL9642876 0.80 PTPN1 (0.64) PTPN1MAPTTDP1KDM4EL3MBTL1
SCHEMBL11129631 0.78 MAPT (0.47) NSD2HSP90AA1HKDC1TLR9IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4460678-A Tellurium imaging composition including improved reductant precursor and method ENERGY CONVERSION DEVICES, INC. (US) 1984-07-17 US claimed
EP-0098020-A2 Imaging film and film-forming composition, method for recording electromagnetic radiation, quinone compounds and method of synthesizing quinone compounds ENERGY CONVERSION DEVICES, INC. (US) 1984-01-11 EP claimed
EP-0100126-B1 METHOD FOR RECORDING ELECTROMAGNETIC RADIATION ENERGY CONVERSION DEVICES, INC. (US) 1988-11-30 EP disclosed
US-4698184-A Tellurium imaging composition including improved reductant precursor and method ENERGY CONVERSION DEVICES, INC. (US) 1987-10-06 US disclosed
US-4592867-A Synthesis method for reductant precursor ENERGY CONVERSION DEVICES, INC. (US) 1986-06-03 US disclosed
EP-0178903-A2 Improved tellurium imaging composition and film including imide or ammonium salt ENERGY CONVERSION DEVICES, INC. (US) 1986-04-23 EP disclosed
EP-0178904-A2 Quinone synthesis ENERGY CONVERSION DEVICES, INC. (US) 1986-04-23 EP disclosed
US-4535055-A DIOLS, QUINONES, ORGANO TELLURIUM COMPOUNDS ENERGY CONVERSION DEVICES, INC. (US) 1985-08-13 US disclosed
US-4532078-A 2,3-Diisopropoxy-1,4-naphthoquinone ENERGY CONVERSION DEVICES, INC. (US) 1985-07-30 US disclosed
US-4460678-A Tellurium imaging composition including improved reductant precursor and method ENERGY CONVERSION DEVICES, INC. (US) 1984-07-17 US disclosed
US-4451556-A Tellurium imaging composition including base ENERGY CONVERSION DEVICES, INC. (US) 1984-05-29 US disclosed
US-4448877-A IMPROVED SPEED ENERGY CONVERSION DEVICES, INC. (US) 1984-05-15 US disclosed
US-4446224-A DIOL, REDUCING AGENT, MATRIX ENERGY CONVERSION DEVICES, INC. (US) 1984-05-01 US disclosed
EP-0100126-A2 Method for recording electromagnetic radiation ENERGY CONVERSION DEVICES, INC. (US) 1984-02-08 EP disclosed
EP-0099146-A2 Film and composition for forming an image and method for recording electromagnetic radiation ENERGY CONVERSION DEVICES, INC. (US) 1984-01-25 EP disclosed
EP-0098019-A2 Imaging film and composition including a tellurium compound and method for recording electromagnetic radiation ENERGY CONVERSION DEVICES, INC. (US) 1984-01-11 EP disclosed
EP-0098020-A2 Imaging film and film-forming composition, method for recording electromagnetic radiation, quinone compounds and method of synthesizing quinone compounds ENERGY CONVERSION DEVICES, INC. (US) 1984-01-11 EP disclosed
EP-0098018-A2 Imaging film and composition employing an organo-metallic compound and method for recording electromagnetic radiation ENERGY CONVERSION DEVICES, INC. (US) 1984-01-11 EP disclosed