SCHEMBL10446166

SCHEMBL10446166

O=C1C(Cl)=C(OCCO)C(=O)c2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.52
DNMT1 P26358 1/20 0.52
DNMT3L Q9UJW3 1/20 0.52
DNMT3A Q9Y6K1 1/20 0.52
HSP90AA1 P07900 3/20 0.51
HKDC1 Q2TB90 2/20 0.51
TLR9 Q9NR96 2/20 0.51
NSD2 O96028 2/20 0.51
CDC25A P30304 6/20 0.50
MAPT P10636 8/20 0.47
LMNA P02545 5/20 0.47
HTT P42858 3/20 0.47
PTPN1 P18031 2/20 0.45
ALDH1A1 P00352 4/20 0.42
RECQL P46063 2/20 0.42
TDP1 Q9NUW8 5/20 0.41
MITF O75030 2/20 0.41
POLB P06746 2/20 0.41
USP2 O75604 1/20 0.41
MAPK1 P28482 5/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10446464 0.81 IDO1 (0.56) IDO1DNMT1DNMT3LDNMT3AHSP90AA1
SCHEMBL10705446 0.81 PTPN1 (0.55) IDO1DNMT1DNMT3LDNMT3AHSP90AA1
Benzene SCHEMBL9714013 0.80 NSD2 (0.58) IDO1DNMT1DNMT3LDNMT3AHSP90AA1
SCHEMBL10707493 0.79 PTPN1 (0.61) IDO1DNMT1DNMT3LDNMT3AHSP90AA1
SCHEMBL10737111 0.75 IDO1 (0.52) IDO1DNMT1DNMT3LDNMT3AHSP90AA1
SCHEMBL15679343 0.73 CDC25B (0.70) HKDC1TLR9CDC25AMAPTLMNA
SCHEMBL11129631 0.72 MAPT (0.47) IDO1DNMT1DNMT3LDNMT3AHSP90AA1
SCHEMBL10959025 0.71 MAPT (0.43) IDO1DNMT1DNMT3LDNMT3AHSP90AA1
SCHEMBL8285443 0.71 MAPT (0.71) IDO1DNMT1DNMT3LDNMT3AHSP90AA1
Dichlon SCHEMBL45723 0.71 IDO1 (1.00) IDO1DNMT1DNMT3LDNMT3AHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4324852-A REDOX COUPLES EASTMAN KODAK COMPANY (US) 1982-04-13 US claimed
US-4195998-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, QUINONE OR CARBAZIDE PHOTOREDUCTANT EASTMAN KODAK COMPANY (US) 1980-04-01 US claimed
EP-0383536-A2 Thermo-sensitive transfer printing medium SEIKO INSTRUMENTS INC. (JP) 1990-08-22 EP disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4171221-A NONSILVER PHOTOGTAPHY EASTMAN KODAK COMPANY (US) 1979-10-16 US disclosed