SCHEMBL10705604

SCHEMBL10705604

CCOC(=O)c1ccsc1N=C=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ALDH1A1 P00352 6/20 0.43
KDM4E B2RXH2 3/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
RECQL P46063 2/20 0.43
THRB P10828 1/20 0.43
HSD17B10 Q99714 4/20 0.41
GAA P10253 4/20 0.40
MAPK1 P28482 1/20 0.40
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
MAPT P10636 4/20 0.39
RAB9A P51151 3/20 0.39
ALOX15 P16050 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10706597 0.83 KMT2A (0.45) TSHRALDH1A1KDM4EMEN1KMT2A
SCHEMBL10713138 0.76 MAPT (0.53) TSHRALDH1A1KDM4EMEN1KMT2A
SCHEMBL1844052 0.75 TSHR (0.57) TSHRALDH1A1KDM4EMEN1KMT2A
SCHEMBL5078857 0.74 TSHR (0.55) TSHRALDH1A1KDM4EMEN1KMT2A
SCHEMBL162212 0.74 TSHR (0.55) TSHRALDH1A1KDM4EMEN1KMT2A
SCHEMBL10713073 0.74 GAA (0.62) TSHRALDH1A1KDM4EMEN1KMT2A
SCHEMBL1773527 0.73 TSHR (0.65) TSHRALDH1A1KDM4EMEN1KMT2A
SCHEMBL10713730 0.73 ADRA2A (0.63) ALDH1A1MEN1KMT2AHSD17B10GAA
SCHEMBL1513079 0.72 TSHR (0.53) TSHRALDH1A1KDM4EMEN1KMT2A
SCHEMBL225275 0.72 ALDH1A1 (0.54) TSHRALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0202538-B1 GROWTH PROMOTING AGENTS BAYER AG (DE) 1988-12-28 EP disclosed
US-4692461-A PLANT PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
EP-0224140-A1 Thienyl urea derivatives BAYER AG (DE) 1987-06-03 EP disclosed
EP-0202538-A1 Growth promoting agents BAYER AG (DE) 1986-11-26 EP disclosed