Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628373 | 0.89 | SLC2A1 (0.43) | HTTALOX15ADRB2SMN1; SMN2ALDH1A1 | |
| SCHEMBL10708295 | 0.84 | CNR1 (0.44) | CNR1CNR2HTTALOX15ALDH1A1 | |
| SCHEMBL9713960 | 0.84 | CNR1 (0.44) | CNR1CNR2HTTALOX15ALDH1A1 | |
| SCHEMBL9657067 | 0.83 | CNR1 (0.43) | CNR1CNR2HTTSMN1; SMN2MAOB | |
| SCHEMBL9627873 | 0.82 | HTT (0.60) | CNR1CNR2HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30003139 | 0.82 | ALOX15 (0.47) | HTTALOX15ADRB2LMNAMAPT | |
| SCHEMBL9627599 | 0.82 | HTT (0.44) | HTTALOX15SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9659324 | 0.81 | CNR1 (0.44) | CNR1CNR2HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9659432 | 0.81 | CNR1 (0.44) | CNR1CNR2HTTSMN1; SMN2MAOB | |
| SCHEMBL10703543 | 0.81 | HTT (0.43) | HTTALOX15ADRB2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |