Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4239989 | 0.86 | TSHR (0.59) | CYP3A4TSHRMMP9MMP8MMP14 | |
| SCHEMBL1982685 | 0.84 | THRB (0.54) | CYP3A4TSHRMMP9MMP8MMP14 | |
| SCHEMBL17091387 | 0.83 | CYP3A4 (0.56) | CYP3A4TSHRMMP9MMP8MMP14 | |
| SCHEMBL26920606 | 0.83 | THRB (0.53) | CYP3A4TSHRMMP9MMP8MMP14 | |
| SCHEMBL985292 | 0.83 | THRB (0.53) | CYP3A4TSHRMMP9MMP8MMP14 | |
| SCHEMBL5452606 | 0.79 | TSHR (0.43) | CYP3A4TSHRMMP9MMP8MMP14 | |
| SCHEMBL546262 | 0.79 | TSHR (0.43) | CYP3A4TSHRMMP9MMP8MMP14 | |
| SCHEMBL9090344 | 0.79 | CYP3A4 (0.58) | CYP3A4TSHRMMP9MMP8MMP14 | |
| SCHEMBL22186939 | 0.78 | TSHR (0.54) | CYP3A4TSHRMMP9MMP8MMP14 | |
| SCHEMBL29109726 | 0.78 | TSHR (0.54) | CYP3A4TSHRMMP9MMP8MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105639-B1 | PRODUCTION OF RESISTOR FROM INSULATING MATERIAL BY LOCAL HEATING | KABUSHIKI KAISHA TOSHIBA (JP) | 1988-01-07 | — | — | EP | disclosed |
| US-4584456-A | Production of resistor from insulating material by local heating | TOKYO SHIBAURA DENKI KABUSHIKI KAISHA (JP) | 1986-04-22 | — | — | US | disclosed |
| EP-0105639-A2 | Production of resistor from insulating material by local heating | KABUSHIKI KAISHA TOSHIBA (JP) | 1984-04-18 | — | — | EP | disclosed |