SCHEMBL1070599

SCHEMBL1070599

OCCCCCCOc1ccc(C=Cc2ccc(OC3CCCCO3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
MAOB P27338 3/20 0.40
MAOA P21397 2/20 0.40
HPGD P15428 1/20 0.39
PPARA Q07869 1/20 0.39
ALB P02768 1/20 0.38
CHRNA7 P36544 2/20 0.38
KCNH2 Q12809 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA10 Q9GZZ6 1/20 0.38
CHRNA9 Q9UGM1 1/20 0.38
APP P05067 7/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1070597 1.00 MEN1 (0.51) MEN1KMT2AMAOBMAOAHPGD
SCHEMBL13083482 0.92 MEN1 (0.57) MEN1KMT2AMAOAHPGDKCNH2
SCHEMBL6706565 0.91 MEN1 (0.55) MEN1KMT2AHPGDKCNH2HRH3
SCHEMBL19844980 0.88 MEN1 (0.55) MEN1KMT2AHPGDKCNH2HRH3
SCHEMBL13089480 0.86 MEN1 (0.52) MEN1KMT2AKCNH2HRH3
SCHEMBL10050874 0.84 MEN1 (0.53) MEN1KMT2AHPGDKCNH2HRH3
SCHEMBL7284022 0.81 MEN1 (0.38) MEN1KMT2AHPGD
SCHEMBL7272729 0.81 MEN1 (0.39) MEN1KMT2AHPGD
SCHEMBL7272735 0.81 MEN1 (0.39) MEN1KMT2AHPGD
SCHEMBL18873508 0.80 MEN1 (0.49) MEN1KMT2AKCNH2HRH3APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2159611-B1 Polymerizable liquid crystal and oriented polymer film SUMITOMO CHEMICAL CO (JP) 2018-01-03 EP disclosed
US-8518299-B2 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2013-08-27 US disclosed
EP-1682930-B1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM SUMITOMO CHEMICAL CO (JP) 2011-01-19 EP disclosed
US-20100267858-A1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM LUB JOHAN 2010-10-21 US disclosed
US-7763330-B2 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2010-07-27 US disclosed
EP-2159611-A1 Polymerizable liquid crystal and oriented polymer film Sumitomo Chemical Company, Limited (JP) 2010-03-03 EP disclosed
US-20070024970-A1 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2007-02-01 US disclosed
EP-1682930-A1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM Koninklijke Philips Electronics N.V. (NL) 2006-07-26 EP disclosed
WO-2005045485-A1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2005-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267858-A1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM ZW10, DSC1, VIM MEN1 342/4885KMT2A 2836/4885MAOB 3146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.