Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13083482 | 0.99 | MEN1 (0.57) | MEN1KMT2AHRH3KCNH2KDM4C | |
| SCHEMBL19844980 | 0.97 | MEN1 (0.55) | MEN1KMT2AHRH3KCNH2KDM4C | |
| SCHEMBL10050874 | 0.93 | MEN1 (0.53) | MEN1KMT2AHRH3KCNH2KDM4C | |
| SCHEMBL13089480 | 0.92 | MEN1 (0.52) | MEN1KMT2AHRH3KCNH2KDM4C | |
| SCHEMBL1070597 | 0.91 | MEN1 (0.51) | MEN1KMT2AHRH3KCNH2HPGD | |
| SCHEMBL1070599 | 0.91 | MEN1 (0.51) | MEN1KMT2AHRH3KCNH2HPGD | |
| SCHEMBL18873508 | 0.87 | MEN1 (0.49) | MEN1KMT2AHRH3KCNH2KDM4C | |
| SCHEMBL24041868 | 0.85 | MEN1 (0.47) | MEN1KMT2AHRH3KCNH2KDM4C | |
| SCHEMBL21247607 | 0.84 | MEN1 (0.50) | MEN1KMT2AHRH3KCNH2KDM4C | |
| SCHEMBL10683385 | 0.82 | MEN1 (0.59) | MEN1KMT2AHRH3KCNH2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023971-A1 | 3,8-Diazabicyclo[3.2.1]octanes and their use in the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023971-A1 | 3,8-Diazabicyclo[3.2.1]octanes and their use in the treatment of cardiac arrhythmias | KCNH1, KCNH2, RYR2 | MEN1 2378/4885KMT2A 3300/4885HRH3 2774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.