Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663661 | 0.91 | THRB (0.44) | THRBTET2 | |
| SCHEMBL17504406 | 0.91 | THRB (0.44) | THRBTET2 | |
| SCHEMBL452156 | 0.87 | TET2 (0.38) | THRBTET2 | |
| SCHEMBL1635423 | 0.82 | THRB (0.44) | THRBTET2 | |
| SCHEMBL1635206 | 0.75 | THRB (0.54) | THRBTET2 | |
| SCHEMBL2404028 | 0.75 | THRB (0.48) | THRBTET2 | |
| SCHEMBL23522592 | 0.73 | THRB (0.58) | THRBTET2 | |
| SCHEMBL12475297 | 0.73 | THRB (0.58) | THRBTET2 | |
| SCHEMBL1907684 | 0.73 | THRB (0.58) | THRBTET2 | |
| SCHEMBL8457919 | 0.73 | THRB (0.58) | THRBTET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103436-B1 | PROCESS FOR PREPARING 5-PERFLUOROALKYL-5,6-DIHYDROURACIL DERIVATIVES AND COMPOUNDS FOR USE THEREIN | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1988-11-17 | — | — | EP | disclosed |
| US-4581452-A | ANTICARCINOGENIC, ANTITUMOR AGENTS; CYCLIZATION | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-04-08 | — | — | US | disclosed |
| EP-0103436-A2 | Process for preparing 5-perfluoroalkyl-5,6-dihydrouracil derivatives and compounds for use therein | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1984-03-21 | — | — | EP | disclosed |