SCHEMBL10706294

SCHEMBL10706294

CC1(F)C(F)(F)C(F)(F)C2(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C12F

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
TDP1 Q9NUW8 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9451902 1.00 MEN1 (0.57) MEN1KMT2ATDP1
SCHEMBL21851606 0.90 MEN1 (0.53) MEN1KMT2ATDP1
SCHEMBL11613184 0.83 MEN1 (0.44) MEN1KMT2ATDP1
SCHEMBL17831505 0.81 MEN1 (0.61) MEN1KMT2ATDP1
SCHEMBL18496397 0.81 MEN1 (0.40) MEN1KMT2ATDP1
SCHEMBL24732508 0.76 MEN1 (0.39) MEN1KMT2ATDP1
SCHEMBL3458732 0.76 MEN1 (0.39) MEN1KMT2ATDP1
SCHEMBL1336247 0.76 MEN1 (0.39) MEN1KMT2ATDP1
SCHEMBL3412014 0.76 MEN1 (0.39) MEN1KMT2ATDP1
SCHEMBL112086 0.76 MEN1 (0.39) MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0101511-B1 METHOD FOR PROVIDING AN OXYGEN BEARING LIQUID TO A BLOOD VESSEL FOR THE PERFORMANCE OF A MEDICAL PROCEDURE TRIMEDYNE LASER SYSTEMS, INC (US) 1988-06-01 EP disclosed
EP-0101511-A4 METHOD FOR PROVIDING AN OXYGEN BEARING LIQUID TO A BLOOD VESSEL FOR THE PERFORMANCE OF A MEDICAL PROCEDURE. LOEB MARVIN P 1984-06-13 EP disclosed
US-4448188-A Method for providing an oxygen bearing liquid to a blood vessel for the performance of a medical procedure LASERSCOPE, INC. (US) 1984-05-15 US disclosed
EP-0101511-A1 METHOD FOR PROVIDING AN OXYGEN BEARING LIQUID TO A BLOOD VESSEL FOR THE PERFORMANCE OF A MEDICAL PROCEDURE. LOEB MARVIN P 1984-02-29 EP disclosed
WO-1983002885-A1 METHOD FOR PROVIDING AN OXYGEN BEARING LIQUID TO A BLOOD VESSEL FOR THE PERFORMANCE OF A MEDICAL PROCEDURE LOEB, MARVIN, P. 1983-09-01 WO disclosed
US-4289499-A BY DETERMINATION OF CRITICAL SOLUTION TEMPERATURE CHILDRENS HOSPITAL MEDICAL CENTER (US) 1981-09-15 US disclosed