Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3698354 | 0.87 | CES1 (0.41) | ALDH1A1CES2CES1TSHRSPHK2 | |
| SCHEMBL1071160 | 0.85 | TSHR (0.41) | TSHRLMNAKDM4E | |
| SCHEMBL2020030 | 0.85 | DGKA (0.48) | CES2CES1TSHRSPHK2SPHK1 | |
| SCHEMBL3804877 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CTSDCES2CES1HDAC3 | |
| SCHEMBL8957558 | 0.84 | SPHK2 (0.52) | ALDH1A1CES2CES1TSHRSPHK2 | |
| SCHEMBL8957562 | 0.84 | SPHK2 (0.52) | ALDH1A1CES2CES1TSHRSPHK2 | |
| SCHEMBL2906934 | 0.84 | SPHK2 (0.52) | ALDH1A1CES2CES1TSHRSPHK2 | |
| Hydrochloric Acid SCHEMBL11572218 | 0.84 | DGKA (0.47) | CES2CES1TSHRSPHK2SPHK1 | |
| SCHEMBL8957576 | 0.84 | SPHK2 (0.52) | ALDH1A1CES2CES1TSHRSPHK2 | |
| SCHEMBL10885536 | 0.84 | SPHK2 (0.52) | ALDH1A1CES2CES1TSHRSPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8278309-B2 | Synthetic mimetics of host defense and uses thereof | POLYMEDIX, INC. (US) | 2012-10-02 | — | — | US | claimed |
| EP-2358380-A1 | SYNTHETIC MIMETICS OF HOST DEFENSE AND USES THEREOF | Polymedix, Inc. (US) | 2011-08-24 | — | — | EP | claimed |
| WO-2010062573-A1 | SYNTHETIC MIMETICS OF HOST DEFENSE AND USES THEREOF | POLYMEDIX, INC. (US) | 2010-06-03 | — | — | WO | claimed |
| US-12491493-B1 | Amine appended bimetallic metal-organic framework (MOF-74) for carbon dioxide capture and method of preparation thereof | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2025-12-09 | — | — | US | disclosed |
| CN-119770470-A | Application of 4-GBA in preparation of medicines for improving infection tolerance of sepsis patients | 海南医学院第二附属医院 | 2025-04-08 | — | — | CN | disclosed |
| CN-118139636-A | Delivery of promoted concentrated antibody formulations using hyaluronidase | 武田药品工业株式会社 | 2024-06-04 | — | — | CN | disclosed |
| CN-111621267-B | Environment-friendly hyperbranched poly-guano acid shale intercalation inhibitor | 西南石油大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-112029769-B | Construction method of Cyp1a1 gene knockout mouse model and application of model in sepsis | 中国人民解放军陆军特色医学中心 | 2022-03-22 | — | — | CN | disclosed |
| CN-112920065-A | Benzil compound and preparation method and application thereof | 上海中医药大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-112029769-A | Construction method of Cyp1a1 gene knockout mouse model and application of model in sepsis | 中国人民解放军陆军特色医学中心 | 2020-12-04 | — | — | CN | disclosed |
| CN-111621267-A | Environment-friendly hyperbranched poly-guano acid shale intercalation inhibitor | 西南石油大学 | 2020-09-04 | — | — | CN | disclosed |
| EP-1867672-A1 | EPOXY RESIN COMPOSITION | Asahi Kasei Chemicals Corporation (JP) | 2007-12-19 | — | — | EP | disclosed |
| CN-101062907-A | Agmatine derivative and medicament usage thereof | POISON MED INST PLA MED ACAD (CN) | 2007-10-31 | — | — | CN | disclosed |
| CN-1834085-A | Trilerium and trilerium marked agmatine and application in biochemistry and medicine research | INST OF TOXIC & MEDICINES A M (CN) | 2006-09-20 | — | — | CN | disclosed |
| EP-1140958-A1 | ANTI-(RETRO)VIRAL CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039139-A1 | ANTI-(RETRO)VIRAL CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2000-07-06 | — | — | WO | disclosed |
| US-5583020-A | IONIZATION; DRUG DELIVERY | RIBOZYME PHARMACEUTICALS, INC. (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0669926-A1 | PERMEABILITY ENHANCERS FOR IONIC THERAPEUTIC POLYMERS | RIBOZYME PHARMACEUTICALS, INC. (US) | 1995-09-06 | — | — | EP | disclosed |
| WO-1994012516-A9 | PERMEABILITY ENHANCERS FOR IONIC THERAPEUTIC POLYMERS | — | 1994-08-04 | — | — | WO | disclosed |
| WO-1994012516-A1 | PERMEABILITY ENHANCERS FOR IONIC THERAPEUTIC POLYMERS | RIBOZYME PHARMACEUTICALS, INC. (US) | 1994-06-09 | — | — | WO | disclosed |