Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.46 |
| ▸ | PGR | P06401 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940208 | 0.91 | NR3C1 (0.48) | NR3C1PGRCYP3A4LMNAMAPT | |
| SCHEMBL11799696 | 0.86 | CYP3A4 (0.60) | NR3C1PGRCYP3A4LMNAMAPT | |
| SCHEMBL10705465 | 0.86 | CYP3A4 (0.60) | NR3C1PGRCYP3A4LMNAMAPT | |
| SCHEMBL10703308 | 0.85 | AR (0.54) | NR3C1PGRCYP3A4LMNAMAPT | |
| SCHEMBL10703509 | 0.84 | NR3C1 (0.52) | NR3C1PGRCYP3A4LMNAMAPT | |
| SCHEMBL10707423 | 0.83 | NR3C1 (0.59) | NR3C1PGRCYP3A4LMNAMAPT | |
| SCHEMBL10704393 | 0.83 | NR3C1 (0.66) | NR3C1PGRCYP3A4LMNAMAPT | |
| SCHEMBL10703728 | 0.83 | CYP3A4 (0.50) | NR3C1PGRCYP3A4LMNAMAPT | |
| SCHEMBL10705476 | 0.81 | NR3C1 (0.69) | NR3C1PGRCYP3A4LMNAMAPT | |
| SCHEMBL11408229 | 0.81 | LMNA (0.68) | NR3C1PGRCYP3A4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153270-B1 | 1-ALPHA, 2-ALPHA-METHYLENE-6-METHYLENE AND 6-ALPHA-METHYL PREGNENES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-07-27 | — | — | EP | disclosed |
| US-4670427-A | ANTIANDROGENS | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-06-02 | — | — | US | disclosed |