SCHEMBL10707233

SCHEMBL10707233

CC(=O)N(O)CCC[C@H](N)C(=O)N(C(=O)[C@@H](N)CCCN(O)C(C)=O)[C@@H](CCCN(O)C(C)=O)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 7/20 0.39
NOS1 P29475 6/20 0.39
NOS3 P29474 5/20 0.39
MEN1 O00255 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
BLM P54132 1/20 0.33
GSR P00390 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3117359 0.82 NOS2 (0.54) NOS2NOS1NOS3MEN1CYP2C19
SCHEMBL5059526 0.82 NOS2 (0.54) NOS2NOS1NOS3MEN1CYP2C19
SCHEMBL5520220 0.82 NOS2 (0.54) NOS2NOS1NOS3MEN1CYP2C19
SCHEMBL1331744 0.77 GSR (0.52) NOS2NOS1NOS3MEN1CYP2C19
SCHEMBL1331746 0.77 GSR (0.52) NOS2NOS1NOS3MEN1CYP2C19
SCHEMBL5556166 0.76 GSR (0.60) GSR
SCHEMBL8931572 0.76 GSR (0.60) GSR
SCHEMBL18043462 0.73 GSR (0.51) GSR
SCHEMBL4349577 0.72 GSR (0.50) NOS2NOS1NOS3CYP1A2CYP3A4
Acetic Acid SCHEMBL25216566 0.71 GSR (0.46) NOS2NOS1NOS3MEN1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0144750-B1 ANTIBIOTICS, METHOD FOR THEIR PREPARATION, THEIR USE AS MEDICINES AND INTERMEDIATES FOR THEIR PREPARATION BAYER AG (DE) 1988-06-08 EP disclosed