Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 8/20 | 0.54 |
| ▸ | NOS1 | P29475 | 6/20 | 0.54 |
| ▸ | NOS3 | P29474 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ARG2 | P78540 | 4/20 | 0.44 |
| ▸ | ARG1 | P05089 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520220 | 1.00 | NOS2 (0.54) | NOS2NOS1NOS3MEN1CYP2C19 | |
| SCHEMBL3117359 | 1.00 | NOS2 (0.54) | NOS2NOS1NOS3MEN1CYP2C19 | |
| SCHEMBL1331744 | 0.94 | GSR (0.52) | NOS2NOS1NOS3MEN1CYP2C19 | |
| SCHEMBL1331746 | 0.94 | GSR (0.52) | NOS2NOS1NOS3MEN1CYP2C19 | |
| SCHEMBL28469394 | 0.82 | NOS2 (0.56) | NOS2NOS1NOS3MEN1CYP2C19 | |
| SCHEMBL10707233 | 0.82 | NOS2 (0.39) | NOS2NOS1NOS3MEN1CYP2C19 | |
| SCHEMBL9713674 | 0.81 | NOS1 (0.51) | NOS2NOS1NOS3MEN1CYP2C19 | |
| SCHEMBL9713664 | 0.81 | NOS1 (0.51) | NOS2NOS1NOS3MEN1CYP2C19 | |
| SCHEMBL9713668 | 0.81 | NOS1 (0.51) | NOS2NOS1NOS3MEN1CYP2C19 | |
| SCHEMBL7220293 | 0.80 | NOS2 (0.54) | NOS2NOS1NOS3MEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080152641-A1 | Inhibitors of Siderophore Biosynthesis in Fungi | AUTRIA WIRTSCHAFTSSERVICE | 2008-06-26 | — | — | US | disclosed |
| EP-1766076-A2 | METHODS FOR TARGET MOLECULE DETECTION USING SIDEROPHORES AND RELATED COMPOSITIONS | Perkinelmer Las, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005123954-A2 | METHODS FOR TARGET MOLECULE DETECTION USING SIDEROPHORES AND RELATED COMPOSITIONS | PERKINELMER LAS, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
| EP-0253245-B1 | BIOLOGICALLY ACTIVE PEPTIDES TAN-866 | Takeda Chemical Industries, Ltd. (JP) | 1992-10-14 | — | — | EP | disclosed |