SCHEMBL10707285

SCHEMBL10707285

CC(C)=CCC/C(C)=C/[CH]O

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.64
KMT2A Q03164 3/20 0.61
MEN1 O00255 2/20 0.56
CYP3A4 P08684 2/20 0.56
ALOX15 P16050 2/20 0.56
NR1I2 O75469 1/20 0.55
LMNA P02545 1/20 0.55
PGR P06401 1/20 0.55
MAPT P10636 2/20 0.54
UGT1A1 P22309 1/20 0.54
SQLE Q14534 6/20 0.52
KDM4E B2RXH2 2/20 0.50
ATM Q13315 1/20 0.50
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10711405 1.00 ALDH1A1 (0.64) ALDH1A1KMT2AMEN1CYP3A4ALOX15
SCHEMBL6229802 0.95 KMT2A (0.70) ALDH1A1KMT2AMEN1CYP3A4ALOX15
SCHEMBL9953423 0.95 KMT2A (0.70) ALDH1A1KMT2AMEN1CYP3A4ALOX15
SCHEMBL28575170 0.82 NR1I2 (0.76) ALDH1A1KMT2AMEN1CYP3A4ALOX15
SCHEMBL25396940 0.80 ALDH1A1 (0.64) ALDH1A1KMT2AMEN1CYP3A4ALOX15
SCHEMBL1618949 0.80 ALDH1A1 (0.64) ALDH1A1KMT2AMEN1CYP3A4ALOX15
SCHEMBL1618947 0.80 ALDH1A1 (0.64) ALDH1A1KMT2AMEN1CYP3A4ALOX15
SCHEMBL27449251 0.79 KMT2A (0.67) ALDH1A1KMT2AMEN1CYP3A4ALOX15
SCHEMBL2896117 0.78 KMT2A (0.73) ALDH1A1KMT2AMEN1CYP3A4ALOX15
SCHEMBL5323634 0.78 ALDH1A1 (0.61) ALDH1A1KMT2AMEN1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9580399-B2 Geranyl flavonoid derivative with improved water solubility, a method for preparing the same, and a method for treating cancer using the same KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2017-02-28 US claimed
US-20160060239-A1 GERANYL FLAVONOID DERIVATIVE WITH IMPROVED WATER SOLUBILITY, A METHOD FOR PREPARING THE SAME, AND A METHOD FOR TREATING CANCER USING THE SAME KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2016-03-03 US claimed
EP-0112727-B1 PROCESS FOR PRODUCING MYRCENOL Takasago Perfumery Co., Ltd. (JP) 1988-04-06 EP claimed
US-4520212-A CATALYTIC DEAMINATING 7-HYDROXY-(GERANYL-OR NERYL-) DIALKYLAMINE 7PALLADIUM-PHOSPHINE COMPLEX CATALYST TAKASAGO PERFUMERY CO., LTD. (JP) 1985-05-28 US claimed
EP-0112727-A2 Process for producing myrcenol Takasago Perfumery Co., Ltd. (JP) 1984-07-04 EP claimed
US-4421613-A TERPENE ALCOHOLS BUSH BOAKE ALLEN (GB) 1983-12-20 US claimed
JP-59118728-A None JP disclosed
JP-54119439-A None JP disclosed
WO-2021105075-A1 DIBENZOPYRAN AMPK ACTIVATOR COMPOUNDS, COMPOSITIONS, METHODS AND USES THEREOF Société des Produits Nestlé S.A. (CH) 2021-06-03 WO disclosed
US-9580399-B2 Geranyl flavonoid derivative with improved water solubility, a method for preparing the same, and a method for treating cancer using the same KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2017-02-28 US disclosed
US-20160060239-A1 GERANYL FLAVONOID DERIVATIVE WITH IMPROVED WATER SOLUBILITY, A METHOD FOR PREPARING THE SAME, AND A METHOD FOR TREATING CANCER USING THE SAME KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2016-03-03 US disclosed
EP-0112727-B1 PROCESS FOR PRODUCING MYRCENOL Takasago Perfumery Co., Ltd. (JP) 1988-04-06 EP disclosed
US-4520212-A CATALYTIC DEAMINATING 7-HYDROXY-(GERANYL-OR NERYL-) DIALKYLAMINE 7PALLADIUM-PHOSPHINE COMPLEX CATALYST TAKASAGO PERFUMERY CO., LTD. (JP) 1985-05-28 US disclosed
JP-S59118728-A PREPARATION OF MYRCENOL TAKASAGO CORP 1984-07-09 JP disclosed
EP-0112727-A2 Process for producing myrcenol Takasago Perfumery Co., Ltd. (JP) 1984-07-04 EP disclosed
JP-S54119439-A NOVEL SUBSTITUTED CYCLOHEXENE DERIVATIVE AND ITS PREPARATION KURARAY CO LTD 1979-09-17 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160060239-A1 GERANYL FLAVONOID DERIVATIVE WITH IMPROVED WATER SOLUBILITY, A METHOD FOR PREPARING THE SAME, AND A METHOD FOR TREATING CANCER USING THE SAME STAT3, JAK2, ILF3 ALDH1A1 3053/4885KMT2A 2990/4885MEN1 3911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.