Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.61 |
| ▸ | SQLE | Q14534 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953423 | 1.00 | KMT2A (0.70) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL10707285 | 0.95 | ALDH1A1 (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL10711405 | 0.95 | ALDH1A1 (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL109310 | 0.84 | KMT2A (0.73) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL29059665 | 0.84 | KMT2A (0.73) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL2841894 | 0.84 | KMT2A (0.73) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL2896117 | 0.84 | KMT2A (0.73) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL23802597 | 0.83 | KMT2A (1.00) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| Squalene SCHEMBL8819997 | 0.83 | KMT2A (1.00) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| Squalene SCHEMBL890053 | 0.83 | KMT2A (1.00) | KMT2AMAPTALDH1A1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733709-B1 | Mutated farnesyldiphosphate synthase capable of synthesizing geranylgeranyldiphosphate and gene coding therefor | TOYOTA MOTOR CO LTD (JP) | 2005-05-11 | — | — | EP | claimed |