SCHEMBL10707481

SCHEMBL10707481

NC(=O)c1cccc(C(=O)n2c3cccc4c3cccc42)c1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.57
MAPT P10636 2/20 0.57
HTT P42858 2/20 0.57
MEN1 O00255 1/20 0.57
ALDH1A1 P00352 1/20 0.57
HPGD P15428 1/20 0.57
KMT2A Q03164 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
P2RX4 Q99571 1/20 0.54
PARP1 P09874 6/20 0.48
ELANE P08246 2/20 0.47
SRC P12931 1/20 0.45
POLB P06746 1/20 0.44
AGTR1 P30556 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL11494225 0.97 MAPT (0.58) LMNAMAPTHTTMEN1ALDH1A1
SCHEMBL4639305 0.87 MAPT (0.69) LMNAMAPTHTTMEN1ALDH1A1
SCHEMBL8023046 0.84 MAPT (0.74) LMNAMAPTHTTMEN1ALDH1A1
SCHEMBL4434522 0.81 PARP1 (0.52) LMNAMAPTMEN1ALDH1A1KMT2A
SCHEMBL8855118 0.79 DHODH (0.45) LMNAMAPTHTTMEN1ALDH1A1
SCHEMBL872109 0.79 P2RX4 (0.81) LMNAMAPTHTTMEN1ALDH1A1
SCHEMBL31021028 0.78 PARP1 (0.73) MAPTMEN1KMT2APARP1POLB
SCHEMBL36694 0.78 PARP1 (0.73) MAPTMEN1KMT2APARP1POLB
Methane SCHEMBL688609 0.76 PARP1 (0.70) MAPTMEN1KMT2APARP1POLB
Water SCHEMBL7768285 0.76 PARP1 (0.70) MAPTMEN1KMT2APARP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0089732-B1 FIBERS AND FIBROUS ASSEMBLY OF WHOLLY AROMATIC POLYAMIDE TEIJIN LIMITED (JP) 1988-01-07 EP disclosed
EP-0098938-B1 CELLULAR AROMATIC POLYAMIDE ARTICLES WITH CLOSED CELLS, AND PROCESS FOR THE PREPARATION THEREOF TEIJIN LIMITED (JP) 1987-08-19 EP disclosed
EP-0086112-B1 PROCESS AND APPARATUS FOR PRODUCING FIBROUS ASSEMBLY TEIJIN LIMITED (JP) 1987-05-20 EP disclosed
US-4552810-A FIBERS, FILMS, INSULATION, TEIJIN LIMITED (JP) 1985-11-12 US disclosed
US-4526735-A Extruding fiber forming polymer through spinneret having numerous openings, passing through spinneret an electric current to give polymer Joule heat required for cutting polymer TEIJIN LIMITED (JP) 1985-07-02 US disclosed
EP-0047091-B1 PROCESS AND MOLDING APPARATUS FOR PRODUCING A FIBROUS ASSEMBLY BY MELT EXTRUSION TEIJIN LIMITED (JP) 1984-05-09 EP disclosed
US-4444911-A HEATING, MOISTURE TEIJIN LIMITED (JP) 1984-04-24 US disclosed
EP-0098938-A2 Cellular aromatic polyamide articles with closed cells, and process for the preparation thereof TEIJIN LIMITED (JP) 1984-01-25 EP disclosed
EP-0089732-A2 Fibers and fibrous assembly of wholly aromatic polyamide TEIJIN LIMITED (JP) 1983-09-28 EP disclosed
EP-0086112-A2 Process and apparatus for producing fibrous assembly TEIJIN LIMITED (JP) 1983-08-17 EP disclosed
US-4399084-A EXTRUSION THROUGH SPINNERET WITH OPENINGS OF SPECIAL OPENING RATIO TEIJIN LIMITED (JP) 1983-08-16 US disclosed
EP-0047091-A1 Process and molding apparatus for producing a fibrous assembly by melt extrusion TEIJIN LIMITED (JP) 1982-03-10 EP disclosed