SCHEMBL4434522

SCHEMBL4434522

NC(=O)c1cccc(C(=O)n2c3ccc2cc3)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 9/20 0.52
TSHR P16473 2/20 0.45
HSD17B10 Q99714 2/20 0.45
POLB P06746 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPT P10636 1/20 0.45
CYP2C19 P33261 1/20 0.45
RECQL P46063 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PARP15 Q460N3 2/20 0.45
PARP10 Q53GL7 2/20 0.45
GAA P10253 1/20 0.44
TNKS O95271 1/20 0.43
PARP14 Q460N5 1/20 0.43
TNKS2 Q9H2K2 1/20 0.43
PARP2 Q9UGN5 1/20 0.43
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29078910 0.83 LCK (0.56) PARP1TSHRHSD17B10L3MBTL1PARP15
SCHEMBL10707481 0.81 LMNA (0.57) PARP1POLBMAPTALDH1A1LMNA
SCHEMBL36694 0.81 PARP1 (0.73) PARP1TSHRHSD17B10POLBCYP3A4
SCHEMBL31021028 0.81 PARP1 (0.73) PARP1TSHRHSD17B10POLBCYP3A4
SCHEMBL8970415 0.81 PARP1 (0.47) PARP1TSHRHSD17B10MAPTPARP15
Benzene SCHEMBL28239358 0.80 MAPT (0.54) PARP1TSHRHSD17B10POLBCYP3A4
SCHEMBL174536 0.79 PARP10 (0.46) PARP1TSHRHSD17B10POLBCYP3A4
Terephthalamide SCHEMBL11494225 0.79 MAPT (0.58) PARP1TSHRHSD17B10POLBCYP3A4
Hydrochloric Acid SCHEMBL1367509 0.79 PARP1 (0.70) PARP1TSHRHSD17B10POLBCYP3A4
Water SCHEMBL7768285 0.79 PARP1 (0.70) PARP1TSHRHSD17B10POLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112661954-A Star polyamide and application thereof 中国石油化工股份有限公司 2021-04-16 CN claimed
CN-117904586-A Positive composite aluminum foil current collector and preparation method thereof 安徽元琛环保科技股份有限公司 2024-04-19 CN disclosed
US-20240084484-A1 METHOD AND DEVICE FOR PREPARING MODIFIED POLY (M-PHENYLENE ISOPHTHALAMIDE) (PMIA) FIBER BY CONTINUOUS POLYMERIZATION-DRY-WET SPINNING Zhuzhou Times New Material Technology Co., Ltd. (CN) 2024-03-14 US disclosed
CN-115175963-A Semi-aromatic polyamide resin composition and molded article thereof 三井化学株式会社 2022-10-11 CN disclosed
CN-112639024-B Thermoplastic resin composition 株式会社可乐丽 2022-08-23 CN disclosed
CN-109642346-B Homogeneous blend of carbon-containing and dyeable flame-retardant fibers 纳幕尔杜邦公司 2022-03-22 CN disclosed
CN-113845657-A Semi-aromatic polyamide resin and preparation method thereof 中仑塑业(福建)有限公司 2021-12-28 CN disclosed
CN-112661954-A Star polyamide and application thereof 中国石油化工股份有限公司 2021-04-16 CN disclosed
CN-112639024-A Thermoplastic resin composition 株式会社可乐丽 2021-04-09 CN disclosed
CN-112367950-A Multilayer wound care device with absorption and fluid transfer properties 美利肯公司 2021-02-12 CN disclosed
US-20090300833-A1 FLAME RESISTANT, SELECTIVELY PERMEABLE LAMINATES E. I. DUPONT DE NEMOURS AND COMPANY (US) 2009-12-10 US disclosed
US-20050008850-A1 Glass flake having high thermal conductivity ELECTROLOCK, INC. (US) 2005-01-13 US disclosed
US-6773793-B2 AN ELECTRICAL INSULATING SHEET IS DISCLOSED. THE SHEET INCLUDES 50-99% D GLASS FLAKES AND 1-50% ADDITIVES. OPTIONAL INGREDIENTS INCLUDE A BONDING AGENT, POROSITY CONTROL AGENT, AND REINFORCING AGENT(S) TO ENHANCE TENSILE STRENGTH. ELECTROLOCK, INC. 2004-08-10 US disclosed
US-20030219581-A1 Glass flake paper ELECTROLOCK, INC. 2003-11-27 US disclosed
EP-0361636-B1 Polyamide-polyarylene sulfide blends AMOCO CORP (US) 1995-01-11 EP disclosed
US-4519873-A PAPERMAKING USING POLYAMIDE OR POLYAMIDEIMIDE MITSUBISHI PAPER MILLS, LTD. (JP) 1985-05-28 US disclosed
EP-0007114-B1 AROMATIC POLYAMIDE FILM AND PROCESS FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 1983-03-16 EP disclosed
EP-0046954-A2 Shaped article of aromatic polyamide TEIJIN LIMITED (JP) 1982-03-10 EP disclosed
US-4291142-A Crosslinked aromatic polyamide film and process for producing the same TEIJIN, LIMITED (JP) 1981-09-22 US disclosed
EP-0007114-A1 Aromatic polyamide film and process for producing the same TEIJIN LIMITED (JP) 1980-01-23 EP disclosed