SCHEMBL10707831

SCHEMBL10707831

Nc1cc(N=Nc2ccc(N=Nc3ccccc3)cc2)ccc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 9/20 0.55
▸ KMT2A Q03164 9/20 0.55
▸ MAPT P10636 5/20 0.55
▸ HSP90AA1 P07900 4/20 0.55
▸ TDP1 Q9NUW8 4/20 0.55
▸ KDM4E B2RXH2 3/20 0.55
▸ MAPK1 P28482 3/20 0.55
▸ RAB9A P51151 4/20 0.54
▸ NPC1 O15118 4/20 0.54
▸ HTT P42858 3/20 0.54
▸ PKM P14618 2/20 0.54
▸ NQO2 P16083 1/20 0.53
▸ ALDH1A1 P00352 4/20 0.52
▸ LMNA P02545 2/20 0.52
▸ HPGD P15428 2/20 0.52
▸ ALOX15 P16050 2/20 0.52
▸ HSD17B10 Q99714 2/20 0.52
▸ USP2 O75604 1/20 0.52
▸ GAA P10253 1/20 0.52
▸ ALOX12 P18054 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9172195 1.00 MEN1 (0.55) MEN1KMT2AMAPTHSP90AA1TDP1
SCHEMBL9172206 1.00 MEN1 (0.55) MEN1KMT2AMAPTHSP90AA1TDP1
SCHEMBL10880159 0.83 L3MBTL1 (0.57) MEN1KMT2AMAPTHSP90AA1TDP1
SCHEMBL10973667 0.82 HSD17B10 (0.61) MEN1KMT2AMAPTHSP90AA1TDP1
SCHEMBL10973668 0.82 HSD17B10 (0.61) MEN1KMT2AMAPTHSP90AA1TDP1
SCHEMBL11698723 0.81 MEN1 (0.61) MEN1KMT2AMAPTHSP90AA1TDP1
SCHEMBL11698720 0.81 MEN1 (0.61) MEN1KMT2AMAPTHSP90AA1TDP1
SCHEMBL11247266 0.78 GLO1 (0.38) MEN1KMT2AMAPTHSP90AA1TDP1
SCHEMBL28321907 0.78 NQO2 (0.73) MEN1KMT2AMAPTHSP90AA1TDP1
SCHEMBL11578943 0.77 HSD17B10 (0.66) MAPTALDH1A1HSD17B10GAASENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0181836-B1 PROCESS FOR IMPROVING THE LIGHT FASTNESS OF DYED LEATHERS CIBA-GEIGY AG (CH) 1988-12-21 — — EP disclosed
EP-0181836-A1 Process for improving the light fastness of dyed leathers CIBA-GEIGY AG (CH) 1986-05-21 — — EP disclosed
US-4331596-A Arylazoarylazo-substituted azo, azomethine 1:2 chromium complex dyes CIBA-GEIGY CORPORATION (US) 1982-05-25 — — US disclosed
EP-0009466-B1 1 : 2-BIS-CHROMIUM-COMPLEX DYESTUFFS FROM POLYAZO- OR DISAZO-AZOMETHINE COMPOUNDS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1982-05-19 — — EP disclosed
US-4311641-A Chromium complexes of mixed azo compounds CIBA-GEIGY CORPORATION (US) 1982-01-19 — — US disclosed
EP-0005207-B1 BIS-1:2 CHROME-DISAZO-BISAZO METHINE DYESTUFFS, THEIR PREPARATION AND USE FOR DYEING OF LEATHER CIBA-GEIGY AG (CH) 1981-12-09 — — EP disclosed
US-4256633-A AZO DYES; AZOMETHINE DYES; WOOL, POLYAMIDES, AND LEATHER CIBA-GEIGY CORPORATION (US) 1981-03-17 — — US disclosed
EP-0009466-A1 1 : 2-Bis-chromium-complex dyestuffs from polyazo- or disazo-azomethine compounds, their preparation and their use CIBA-GEIGY AG (CH) 1980-04-02 — — EP disclosed
EP-0005207-A2 Bis-1:2 chrome-disazo-bisazo methine dyestuffs, their preparation and use for dyeing of leather CIBA-GEIGY AG (CH) 1979-11-14 — — EP disclosed
US-4116952-A POLYAMIDES CIBA-GEIGY CORPORATION (US) 1978-09-26 — — US disclosed
US-4033942-A Chromium complex dye, including azo and azo methine dye compounds CIBA-GEIGY AG (CH) 1977-07-05 — — US disclosed
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