Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28545064 | 0.83 | ALDH1A1 (0.55) | TDP1MAPK1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL28396278 | 0.82 | TDP1 (0.41) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL10709940 | 0.80 | TDP1 (0.66) | TDP1CYP3A4SMN1; SMN2MAPTRAB9A | |
| Benzene SCHEMBL27257767 | 0.79 | TDP1 (0.89) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL8526630 | 0.78 | TDP1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL5097 | 0.78 | — | — | |
| SCHEMBL8603841 | 0.76 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL5601373 | 0.76 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL21840887 | 0.76 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Methane SCHEMBL22289589 | 0.76 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182155-B1 | MULTI-ACTIVE PHOTOCONDUCTIVE INSULATING ELEMENTS EXHIBITING VERY HIGH ELECTROPHOTOGRAPHIC SPEED AND PANCHROMATIC SENSITIVITY AND METHOD FOR THEIR MANUFACTURE | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-12-28 | — | — | EP | disclosed |
| US-4618560-A | Multi-active photoconductive insulating elements exhibiting very high electrophotographic speed and panchromatic sensitivity and method for their manufacture | EASTMAN KODAK COMPANY (US) | 1986-10-21 | — | — | US | disclosed |
| EP-0182155-A1 | Multi-active photoconductive insulating elements exhibiting very high electrophotographic speed and panchromatic sensitivity and method for their manufacture | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-05-28 | — | — | EP | disclosed |
| US-4578334-A | Multi-active photoconductive insulating elements and method for their manufacture | EASTMAN KODAK COMPANY (US) | 1986-03-25 | — | — | US | disclosed |