Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 15/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 15/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8982370 | 0.84 | SLC6A4 (0.41) | SLC6A4SLC6A3SLC6A2MEN1KMT2A | |
| SCHEMBL10591071 | 0.80 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6891431 | 0.79 | SLC6A3 (0.40) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL10589716 | 0.79 | SLC6A4 (0.62) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5904402 | 0.79 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11524015 | 0.78 | SLC6A4 (0.63) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL10591604 | 0.77 | SLC6A4 (0.60) | SLC6A4SLC6A3SLC6A2TSHR | |
| SCHEMBL30968977 | 0.77 | SLC6A4 (0.40) | SLC6A4SLC6A3SLC6A2ALDH1A1 | |
| SCHEMBL10586709 | 0.76 | SLC6A3 (0.43) | SLC6A4SLC6A3SLC6A2TSHRALDH1A1 | |
| SCHEMBL10009374 | 0.72 | CYP3A4 (0.63) | SLC6A4SLC6A3SLC6A2NQO1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184012-B1 | LIQUID CRYSTAL COMPOSITIONS | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |