SCHEMBL11524015

SCHEMBL11524015

CCCC(C)C1(c2ccc(-c3ccccc3)cc2)CCCCC1

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 14/20 0.63
SLC6A3 Q01959 14/20 0.63
SLC6A2 P23975 6/20 0.63
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
KCNH2 Q12809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10590633 0.85 SLC6A4 (0.46) SLC6A4SLC6A3SLC6A2NPC1RAB9A
SCHEMBL10586709 0.83 SLC6A3 (0.43) SLC6A4SLC6A3SLC6A2KCNH2
SCHEMBL11526231 0.82 SLC6A4 (0.43) SLC6A4SLC6A3SLC6A2NPC1RAB9A
SCHEMBL10768525 0.82 SLC6A4 (0.46) SLC6A4SLC6A3SLC6A2
SCHEMBL11524866 0.82 SLC6A4 (0.46) SLC6A4SLC6A3SLC6A2NPC1RAB9A
SCHEMBL10591071 0.81 SLC6A4 (0.43) SLC6A4SLC6A3SLC6A2
SCHEMBL27262560 0.81 SLC6A4 (0.46) SLC6A4SLC6A3SLC6A2
SCHEMBL10589716 0.80 SLC6A4 (0.62) SLC6A4SLC6A3SLC6A2
Hydrochloric Acid SCHEMBL1778 0.78 SLC6A4 (0.57) SLC6A4SLC6A3SLC6A2NPC1RAB9A
SCHEMBL6891431 0.78 SLC6A3 (0.40) SLC6A4SLC6A3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4154697-A Liquid crystalline hexahydroterphenyl derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1979-05-15 US disclosed