Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3150564 | 0.79 | CYP2A6 (0.38) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL5034793 | 0.79 | CYP1A2 (0.38) | ESR1ESR2CYP1A2LMNAMEN1 | |
| SCHEMBL28433291 | 0.76 | CYP1A2 (0.40) | ESR1ESR2CYP1A2LMNAMEN1 | |
| SCHEMBL9365805 | 0.72 | CYP1A2 (0.42) | CYP1A2MEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL5034862 | 0.71 | CYP1A2 (0.39) | ESR1ESR2CYP1A2LMNAMEN1 | |
| SCHEMBL4670596 | 0.71 | LCK (0.36) | CYP1A2LMNAMEN1POLBKMT2A | |
| SCHEMBL1533447 | 0.70 | CYP1A2 (0.57) | ESR1ESR2CYP1A2LMNAMEN1 | |
| SCHEMBL232794 | 0.70 | ALDH1A1 (0.43) | CYP1A2POLBHSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL6184269 | 0.69 | MPL (0.39) | CYP1A2LMNAMEN1POLBKMT2A | |
| SCHEMBL28918125 | 0.68 | PTGS1 (0.39) | LMNAMEN1POLBKMT2AHNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272644-A2 | Intermediates and their use in the synthesis of organic compounds | ZAMBON S.p.A. (IT) | 1988-06-29 | — | — | EP | claimed |