SCHEMBL5034862

SCHEMBL5034862

Oc1ccc2c(ccc3c(O)[c]ccc32)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.39
LMNA P02545 2/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38
HNF4A P41235 1/20 0.37
ESR1 P03372 9/20 0.36
ESR2 Q92731 9/20 0.36
CYP3A4 P08684 2/20 0.36
ALOX15 P16050 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TSHR P16473 1/20 0.36
HIF1A Q16665 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ABL1 P00519 1/20 0.34
ABCB1 P08183 1/20 0.34
BCR P11274 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5032930 0.89 MCL1 (0.37) CYP1A2LMNAESR1ESR2CYP3A4
SCHEMBL5034793 0.86 CYP1A2 (0.38) CYP1A2LMNAMEN1POLBKMT2A
SCHEMBL1692369 0.81 CYP1A2 (0.55) CYP1A2LMNAMEN1POLBKMT2A
SCHEMBL29899643 0.81 CYP1A2 (0.55) CYP1A2LMNAMEN1POLBKMT2A
SCHEMBL1533447 0.78 CYP1A2 (0.57) CYP1A2LMNAMEN1POLBKMT2A
SCHEMBL5031460 0.78 MCL1 (0.40) CYP1A2LMNAESR1ESR2CYP3A4
SCHEMBL2145668 0.76
SCHEMBL28433291 0.74 CYP1A2 (0.40) CYP1A2LMNAMEN1POLBKMT2A
SCHEMBL6369167 0.72 CYP1A2 (0.50) CYP1A2LMNAMEN1POLBKMT2A
SCHEMBL27289927 0.71 HPRT1 (0.64) CYP1A2MEN1KMT2AHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080262127-A1 FLAME RESISTANT RESIN COMPOSITION CHANG CHUN PLASTICS CO., LTD. (TW) 2008-10-23 US disclosed