SCHEMBL4592642

SCHEMBL4592642

O=C(O)C(O)(c1ccccc1)c1cccc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 5/20 0.52
KIF11 P52732 1/20 0.47
ACP3 P15309 1/20 0.46
CYP2C19 P33261 5/20 0.45
CYP1A2 P05177 4/20 0.45
HSD17B10 Q99714 3/20 0.45
CYP2D6 P10635 3/20 0.45
HPGD P15428 3/20 0.45
HIF1A Q16665 2/20 0.45
NR4A1 P22736 1/20 0.44
NR4A2 P43354 1/20 0.44
NR4A3 Q92570 1/20 0.44
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 3/20 0.42
TDP1 Q9NUW8 2/20 0.41
PPARG P37231 2/20 0.40
PPARA Q07869 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CFTR P13569 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10708482 0.81 KDM4E (0.49) CYP2C9KIF11ACP3CYP2C19CYP1A2
Benzylic Acid SCHEMBL7066 0.80 CYP2C9 (0.74) CYP2C9CYP2C19CYP1A2CYP2D6HIF1A
SCHEMBL11601001 0.80 KIF11 (0.48) CYP2C9KIF11ACP3CYP2C19CYP1A2
Benzylic Acid SCHEMBL1681667 0.78 CYP2C9 (0.71) CYP2C9CYP2C19CYP1A2CYP2D6HIF1A
Benzylic Acid SCHEMBL1680669 0.78 CYP2C9 (0.71) CYP2C9CYP2C19CYP1A2CYP2D6HIF1A
Benzylic Acid SCHEMBL11049826 0.78 CYP2C9 (0.71) CYP2C9CYP2C19CYP1A2CYP2D6HIF1A
Benzylic Acid SCHEMBL9181980 0.78 CYP2C9 (0.71) CYP2C9CYP2C19CYP1A2CYP2D6HIF1A
Benzylic Acid SCHEMBL2810363 0.78 CYP2C9 (0.71) CYP2C9CYP2C19CYP1A2CYP2D6HIF1A
Benzylic Acid SCHEMBL20957595 0.78 CYP2C9 (0.71) CYP2C9CYP2C19CYP1A2CYP2D6HIF1A
Benzylic Acid SCHEMBL5705762 0.78 CYP2C9 (0.71) CYP2C9CYP2C19CYP1A2CYP2D6HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7442485-B2 Lithographic process involving on press development FUJIFILM CORPORATION (JP) 2008-10-28 US disclosed
EP-1484177-B1 Lithographic process involving on press development FUJIFILM CORP (JP) 2007-08-29 EP disclosed
US-20050016402-A1 Lithographic process involving on press development FUJI PHOTO FILM CO., LTD. 2005-01-27 US disclosed
EP-1484177-A2 Lithographic process involving on press development FUJI PHOTO FILM CO., LTD. (JP) 2004-12-08 EP disclosed