Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771021 | 0.98 | MAPT (0.59) | MAPTRXFP1HSD17B10DPP4L3MBTL1 | |
| SCHEMBL27446088 | 0.88 | THRA (0.66) | MAPTRXFP1HSD17B10DPP4L3MBTL1 | |
| SCHEMBL7829240 | 0.88 | DPP4 (0.65) | MAPTRXFP1HSD17B10DPP4L3MBTL1 | |
| SCHEMBL6556728 | 0.83 | THRA (0.55) | DPP4L3MBTL1THRATHRBNPC1 | |
| SCHEMBL11109330 | 0.83 | CYP4A11 (0.53) | HSD17B10DPP4L3MBTL1ALDH1A1THRA | |
| SCHEMBL7822245 | 0.82 | HSD17B10 (0.68) | MAPTRXFP1HSD17B10DPP4L3MBTL1 | |
| SCHEMBL31512079 | 0.82 | L3MBTL1 (0.71) | MAPTRXFP1HSD17B10DPP4L3MBTL1 | |
| SCHEMBL6938543 | 0.82 | THRA (0.77) | MAPTALDH1A1THRATHRB | |
| SCHEMBL9077531 | 0.82 | THRA (0.68) | L3MBTL1ALDH1A1THRATHRB | |
| SCHEMBL13730713 | 0.82 | THRA (0.77) | MAPTALDH1A1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745076-A | Ruthenium complexes useful as carriers for immunologically active materials | HOFFMANN-LA ROCHE INC. (US) | 1988-05-17 | — | — | US | disclosed |