SCHEMBL1070923

SCHEMBL1070923

C[SiH](C)[Ti](Cl)(Cl)(NC(C)(C)C)C1C=Cc2ccccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6466503 0.83
SCHEMBL6533802 0.81
SCHEMBL3227148 0.81
SCHEMBL6465279 0.81
SCHEMBL5853118 0.80 ALDH1A1 (0.31)
SCHEMBL6067475 0.79
SCHEMBL5853694 0.79 SIGMAR1 (0.31)
SCHEMBL5852593 0.78 MEN1 (0.30)
SCHEMBL7647267 0.78 SIGMAR1 (0.30)
SCHEMBL6067340 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1824888-B1 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2017-01-18 EP disclosed
EP-1740626-B1 CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE BASELL POLYOLEFINE GMBH (DE) 2014-10-22 EP disclosed
US-7973114-B2 Monocyclopentadienyl complexes BASELL POLYOLEFINE GMBH (DE) 2011-07-05 US disclosed
EP-1861409-B1 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2011-01-19 EP disclosed
US-7795167-B2 Cyclopentadienyl complexes of group 6 substituted by silyl halides BASELL POLYOLEFINE GMBH (DE) 2010-09-14 US disclosed
US-7776980-B2 Monocyclopentadienyl complexes BASELL POLYOLEFINE GMBH (DE) 2010-08-17 US disclosed
EP-1572359-B1 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2010-04-28 EP disclosed
US-7671148-B2 Mixing organic transition metal compounds, hydrolyzed organoaluminum compound, and solvent, then impregnating dry porous support BASELL POLYOLEFINE GMBH (DE) 2010-03-02 US disclosed
US-7629464-B2 polymerization catalyst for the polymerization of olefins; molecular weight control of polyethylene, ethylene-hexene copolymer; addition polymerization; 1-(diisopropyl(2-oxypyridine)silyl)-3-methylcyclopentadienyl)chromium dichloride BASELL POLYOLEFINE GMBH (DE) 2009-12-08 US disclosed
US-7544826-B2 Monocyclopentadienyl complexes BASELL POLYOLEFINE GMBH (DE) 2009-06-09 US disclosed
WO-2004104052-A1 TRANSITION-METAL COMPLEXES WITH TRIDENTATE, NITROGEN-CONTAINING LIGANDS BASELL POLYOLEFINE GMBH (DE) 2004-12-02 WO disclosed
WO-2004056482-A1 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2004-07-08 WO disclosed
WO-2004056481-A1 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2004-07-08 WO disclosed
WO-2004020479-A2 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2004-03-11 WO disclosed
WO-2004018489-A1 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2004-03-04 WO disclosed
EP-0849292-B1 Olefin polymerisation catalysts and processes for producing olefin polymers TOSOH CORP (JP) 2002-08-21 EP disclosed
US-6110858-A AN OLEFIN POLYMERIZATION CATALYST CONSISTS OF A TRANSITION METAL COMPOUND, A MODIFIED CLAY COMPOUND CONTAINING CLAY MINERAL AND AN AMINE COMPOUND AND AN ORGANOALUMINUM COMPOUND TOSOH CORPORATION (JP) 2000-08-29 US disclosed
US-6034187-A Catalyst for olefin polymerization and process for production of olefin polymer TOSOH CORPORATION (JP) 2000-03-07 US disclosed
EP-0881232-A1 Catalyst for olefin polymerization and process for production of olefin polymer TOSOH CORPORATION (JP) 1998-12-02 EP disclosed
EP-0849292-A1 Olefin polymerisation catalysts and processes for producing olefin polymers TOSOH CORPORATION (JP) 1998-06-24 EP disclosed