SCHEMBL10709581

SCHEMBL10709581

CC[SiH2]Nc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
TDP1 Q9NUW8 4/20 0.39
ALDH1A1 P00352 3/20 0.39
HSD17B10 Q99714 2/20 0.39
CTSD P07339 1/20 0.39
GAA P10253 3/20 0.38
PTGS2 P35354 2/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
PTGS1 P23219 1/20 0.38
SLC6A2 P23975 1/20 0.38
MAPK1 P28482 1/20 0.38
HTR2B P41595 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MAPT P10636 3/20 0.37
IDO1 P14902 2/20 0.36
TP53 P04637 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18991482 0.81 TSHR (0.39) TSHRTDP1ALDH1A1HSD17B10CTSD
SCHEMBL13551147 0.70
SCHEMBL4892687 0.70 CYP1A2 (0.38) TSHRTDP1ALDH1A1HSD17B10CTSD
SCHEMBL17409617 0.69 ALDH1A1 (0.50) TSHRTDP1ALDH1A1HSD17B10CTSD
SCHEMBL30814267 0.69 ALDH1A1 (0.50) TSHRTDP1ALDH1A1HSD17B10CTSD
SCHEMBL234292 0.67 SIGMAR1 (0.41) TSHRTDP1ALDH1A1HSD17B10CTSD
Diphenylamine SCHEMBL8204165 0.67 HSD17B10 (0.75) TSHRTDP1ALDH1A1HSD17B10GAA
SCHEMBL10713569 0.67 CYP3A4 (0.48) TDP1ALDH1A1GAAALOX12MAPT
SCHEMBL10359187 0.67 MAPT (0.44) TSHRTDP1ALDH1A1HSD17B10CTSD
SCHEMBL17046019 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390410-B1 METHODS OF MAKING HIGH PURITY TRISILYLAMINE NATA SEMICONDUCTOR MAT CO LTD (CN) 2022-02-02 EP disclosed
US-11111256-B2 High purity trisilylamine, methods of making, and use JIANGSU NATA OPTO-ELECTRONIC MATERIALS CO. LTD. (CN) 2021-09-07 US disclosed
CN-108602839-B A process for preparing an organoaminosilane; method for producing silylamines from organoaminosilanes 南大光电半导体材料有限公司 2021-06-29 CN disclosed
CN-108602840-B High purity trisilylamine, preparation method and use 南大光电半导体材料有限公司 2021-05-28 CN disclosed
US-10875877-B2 Method for making an organoaminosilane; a method for making a silylamine from the organoaminosilane DOW SILICONES CORPORATION (US) 2020-12-29 US disclosed
EP-3390411-B1 METHOD FOR MAKING AN ORGANOAMINOSILANE; A METHOD FOR MAKING A SILYLAMINE FROM THE ORGANOAMINOSILANE DDP SPECIALTY ELECTRONIC MAT US 9 LLC (US) 2020-09-30 EP disclosed
US-20200262849-A1 HIGH PURITY TRISILYLAMINE, METHODS OF MAKING, AND USE DOW SILICONES CORPORATION (US) 2020-08-20 US disclosed
US-20190352315-A1 METHOD FOR MAKING AN ORGANOAMINOSILANE; A METHOD FOR MAKING A SILYLAMINE FROM THE ORGANOAMINOSILANE DOW SILICONES CORPORATION (US) 2019-11-21 US disclosed
EP-3390410-A1 HIGH PURITY TRISILYLAMINE, METHODS OF MAKING, AND USE Dow Corning Corporation (US) 2018-10-24 EP disclosed
EP-3390411-A1 METHOD FOR MAKING AN ORGANOAMINOSILANE; A METHOD FOR MAKING A SILYLAMINE FROM THE ORGANOAMINOSILANE Dow Corning Corporation (US) 2018-10-24 EP disclosed
WO-2017106625-A1 HIGH PURITY TRISILYLAMINE, METHODS OF MAKING, AND USE DOW CORNING CORPORATION (US) 2017-06-22 WO disclosed
WO-2017106632-A1 METHOD FOR MAKING AN ORGANOAMINOSILANE; A METHOD FOR MAKING A SILYLAMINE FROM THE ORGANOAMINOSILANE DOW CORNING CORPORATION (US) 2017-06-22 WO disclosed
EP-0112434-B1 HYDROGEN BEARING SILYL CARBAMATES UNION CARBIDE CORPORATION (US) 1988-08-17 EP disclosed