Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 12/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29635068 | 0.78 | FOLH1 (0.50) | FOLH1GSRCPB2RNPEPACE | |
| SCHEMBL9181564 | 0.75 | CPB2 (0.55) | FOLH1GSRCPB2 | |
| SCHEMBL9181567 | 0.75 | CPB2 (0.55) | FOLH1GSRCPB2 | |
| SCHEMBL5736086 | 0.74 | CPB2 (0.57) | FOLH1CPB2 | |
| SCHEMBL31555916 | 0.73 | FOLH1 (0.56) | FOLH1GSRCPB2RNPEPSLC6A5 | |
| SCHEMBL29894486 | 0.73 | FOLH1 (0.59) | FOLH1GSRCPB2RNPEPSLC6A5 | |
| SCHEMBL29390540 | 0.73 | FOLH1 (0.59) | FOLH1GSRCPB2RNPEPSLC6A5 | |
| SCHEMBL10611606 | 0.73 | FOLH1 (0.44) | FOLH1GSRCPB2RNPEPACE | |
| SCHEMBL10611602 | 0.73 | FOLH1 (0.44) | FOLH1GSRCPB2RNPEPACE | |
| SCHEMBL1054672 | 0.71 | FOLH1 (0.58) | FOLH1GSRCPB2RNPEPSLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0097031-B1 | NONAPEPTIDE AND DECAPEPTIDE ANALOGS OF LHRH USEFUL AS LHRH ANTAGONISTS, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1988-09-21 | — | — | EP | disclosed |
| EP-0097031-A2 | Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists, their preparation and compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1983-12-28 | — | — | EP | disclosed |