Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 17/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181564 | 0.98 | CPB2 (0.55) | CPB2FOLH1 | |
| SCHEMBL9181567 | 0.98 | CPB2 (0.55) | CPB2FOLH1 | |
| SCHEMBL29635068 | 0.92 | FOLH1 (0.50) | CPB2FOLH1 | |
| SCHEMBL10611606 | 0.86 | FOLH1 (0.44) | CPB2FOLH1 | |
| SCHEMBL10611602 | 0.86 | FOLH1 (0.44) | CPB2FOLH1 | |
| SCHEMBL17453157 | 0.86 | CPB2 (0.47) | CPB2SMN1; SMN2 | |
| SCHEMBL22054642 | 0.86 | CPB2 (0.47) | CPB2SMN1; SMN2 | |
| SCHEMBL22054574 | 0.84 | CPB2 (0.45) | CPB2SMN1; SMN2 | |
| SCHEMBL5530162 | 0.84 | SMN1; SMN2 (0.47) | CPB2SMN1; SMN2 | |
| SCHEMBL2244922 | 0.79 | EPHX2 (0.42) | CPB2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112284-B1 | PIPERAZINE-4-PHENYL DERIVATIVES AS INHIBITORS OF THE INTERACTION BETWEEN MDM2 AND P53 | ASTRAZENECA AB (SE) | 2006-04-19 | — | — | EP | claimed |