Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14894349 | 0.94 | KMT2A (0.55) | KDM4CKMT2AMEN1NPC1RAB9A | |
| SCHEMBL620675 | 0.87 | KDM4C (0.54) | KDM4CKMT2AMEN1NPC1RAB9A | |
| SCHEMBL6072144 | 0.84 | L3MBTL1 (0.55) | KDM4CKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3504843 | 0.84 | MAOB (0.63) | KDM4CKMT2AMEN1NPC1RAB9A | |
| SCHEMBL27983390 | 0.84 | KDM4C (0.51) | KDM4CKMT2AMEN1NPC1RAB9A | |
| SCHEMBL14691569 | 0.83 | KDM4C (0.47) | KDM4CKMT2AMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL10710861 | 0.83 | MAOB (0.61) | KDM4CKMT2AMEN1NPC1RAB9A | |
| SCHEMBL6072210 | 0.82 | HIF1A (0.59) | NPC1RAB9AMAPT | |
| SCHEMBL14904964 | 0.82 | KMT2A (0.52) | KDM4CKMT2AMEN1NPC1RAB9A | |
| SCHEMBL27918571 | 0.82 | ALDH1A1 (0.52) | KDM4CKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764522-A | ANTIDEPRESSANT, ANTIPARKINSON DISEASE | HOFFMANN-LA ROCHE INC. (US) | 1988-08-16 | — | — | US | disclosed |