Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | NQO1 | P15559 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28716052 | 0.86 | BRAF (0.50) | CA12CA9ALDH1A1KDM4ELMNA | |
| SCHEMBL8083350 | 0.84 | CA12 (0.53) | CA12CA9ALDH1A1KDM4ELMNA | |
| SCHEMBL13506406 | 0.84 | CA12 (0.53) | CA12CA9ALDH1A1KDM4ELMNA | |
| SCHEMBL27212655 | 0.81 | CA12 (0.46) | CA12CA9ALDH1A1KDM4ELMNA | |
| SCHEMBL2028247 | 0.80 | ALDH1A1 (0.50) | CA12CA9ALDH1A1KDM4ELMNA | |
| SCHEMBL2522178 | 0.80 | ALDH1A1 (0.50) | CA12CA9ALDH1A1KDM4ELMNA | |
| SCHEMBL7753264 | 0.80 | CA12 (0.57) | CA12CA9ALDH1A1KDM4ELMNA | |
| SCHEMBL19285589 | 0.79 | GAA (0.62) | CA12CA9ALDH1A1KDM4ELMNA | |
| Zinc Ion SCHEMBL29660558 | 0.78 | ALDH1A1 (0.48) | CA12CA9ALDH1A1KDM4ELMNA | |
| SCHEMBL29901650 | 0.77 | CA12 (0.73) | CA12CA9ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121995-B1 | PEPTIDES | KOWA COMPANY, LTD. (JP) | 1988-09-28 | — | — | EP | disclosed |
| US-4487718-A | FOR HEMOSTATIC DISORDERS AND THROMBOSIS | KOWA COMPANY, LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| EP-0121995-A2 | Peptides | KOWA COMPANY, LTD. (JP) | 1984-10-17 | — | — | EP | disclosed |