Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711607 | 0.74 | KMT2A (0.44) | KMT2ARAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL28491071 | 0.71 | KMT2A (0.62) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL17673999 | 0.69 | KMT2A (0.71) | KMT2ARAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL31588107 | 0.69 | KMT2A (0.71) | KMT2ARAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL9431223 | 0.68 | KMT2A (0.46) | KMT2ARAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL195311 | 0.68 | ALDH1A1 (0.62) | KMT2ARAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL6551442 | 0.68 | ALDH1A1 (0.61) | KMT2ARAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL2289848 | 0.68 | ALDH1A1 (0.61) | KMT2ARAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL17673952 | 0.68 | KMT2A (0.54) | KMT2ARAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL8198293 | 0.67 | KMT2A (0.60) | KMT2ARAB9ANPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |