Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666091 | 0.89 | TDP1 (0.44) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL465969 | 0.76 | TDP1 (0.61) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| Phosphine SCHEMBL28775755 | 0.74 | TDP1 (0.58) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL8026287 | 0.74 | SMN1; SMN2 (0.39) | L3MBTL1LMNAMAPK1MEN1KMT2A | |
| SCHEMBL28802086 | 0.74 | NAPRT (0.36) | L3MBTL1POLBNAPRTMEN1THRB | |
| SCHEMBL10866718 | 0.73 | NAPRT (0.33) | CYP2D6NAPRT | |
| SCHEMBL270836 | 0.73 | SLC6A2 (0.44) | HDAC1HDAC8HDAC6KMT2ACES2 | |
| SCHEMBL5865581 | 0.73 | KMT2A (0.47) | HDAC1HDAC8HDAC6KMT2ACES2 | |
| SCHEMBL28854086 | 0.72 | TRPA1 (0.38) | L3MBTL1POLBLMNANAPRT | |
| SCHEMBL11019672 | 0.72 | TRPA1 (0.38) | L3MBTL1POLBLMNANAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149426-B1 | MICROBIZIDES | CIBA-GEIGY AG (CH) | 1988-05-04 | — | — | EP | disclosed |
| EP-0077479-A2 | Phenoxyphenyl-azolylmethyl ketones and carbinols, process for their preparation and their use as fungicides and intermediates | BAYER AG (DE) | 1983-04-27 | — | — | EP | disclosed |