SCHEMBL465969

SCHEMBL465969

O=C(C(c1ccccc1)c1ccccc1)C(c1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
HDAC3 O15379 1/20 0.58
HDAC4 P56524 1/20 0.58
HDAC1 Q13547 1/20 0.58
HDAC7 Q8WUI4 1/20 0.58
HDAC2 Q92769 1/20 0.58
HDAC10 Q969S8 1/20 0.58
HDAC11 Q96DB2 1/20 0.58
HDAC8 Q9BY41 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
HDAC9 Q9UKV0 1/20 0.58
HDAC5 Q9UQL6 1/20 0.58
CTSD P07339 1/20 0.56
CYP2D6 P10635 1/20 0.55
SRC P12931 1/20 0.55
POLB P06746 1/20 0.54
LMNA P02545 3/20 0.52
MAPK1 P28482 1/20 0.52
CES2 O00748 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL28775755 0.97 TDP1 (0.58) TDP1L3MBTL1HDAC3HDAC4HDAC1
SCHEMBL5132036 0.88 CNR1 (0.54) TDP1L3MBTL1HDAC3HDAC4HDAC1
SCHEMBL7073016 0.86 CNR1 (0.56) TDP1L3MBTL1HDAC3HDAC4HDAC1
SCHEMBL9307280 0.86 L3MBTL1 (0.48) TDP1L3MBTL1HDAC3HDAC4HDAC1
SCHEMBL16781990 0.86 CNR1 (0.56) TDP1L3MBTL1HDAC3HDAC4HDAC1
SCHEMBL27545340 0.86 HDAC3 (0.53) TDP1L3MBTL1HDAC3HDAC4HDAC1
SCHEMBL888681 0.85 L3MBTL1 (0.52) TDP1L3MBTL1HDAC3HDAC4HDAC1
SCHEMBL27474118 0.83 L3MBTL1 (0.50) TDP1L3MBTL1HDAC3HDAC4HDAC1
Diphenylacetic Acid SCHEMBL8513250 0.82 SRC (0.62) TDP1L3MBTL1HDAC3HDAC4HDAC1
Diphenylacetic Acid SCHEMBL38022 0.82 SRC (0.62) TDP1L3MBTL1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 714 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118908898-A Efficient synthesis method of 3,4, 6-triaryl substituted pyridazine compound 温州大学 2024-11-08 CN claimed
CN-107722146-B Method for producing solid polyaluminoxane composition 三井化学株式会社 2021-02-26 CN claimed
CN-109791373-A Index matching additives for photocurable compositions 英默里斯筛选矿物公司 2019-05-21 CN claimed
CN-109582092-A Mobile terminal assists use device and digital video interactive 深圳市科迈爱康科技有限公司 2019-04-05 CN claimed
CN-105131218-B A kind of method for improving elastomer dielectric properties 北京化工大学 2018-06-29 CN claimed
CN-108084384-A A kind of polyurethane-type polymeric diphenylmethane ketone photoinitiator 韩会义 2018-05-29 CN claimed
CN-107502127-A A kind of fluorine-containing lubricant coating and its preparation method and application 济南大学 2017-12-22 CN claimed
CN-107163206-A The preparation of polymeric diphenylmethane first ketone compounds and its application in anti-light pollution plastics 句容亿格纳米材料厂 2017-09-15 CN claimed
CN-106348990-A Method for synthesizing 1,2,2-triaryl ethyl ketone and derivatives thereof 兰州大学 2017-01-25 CN claimed
CN-105647257-A Water-based radiation-cured coating and use thereof 珠海市佳伟力环保科技有限公司 2016-06-08 CN claimed
CN-1430607-A Benzophenones as inhibitors of IL-1 beta and TNF-alpha LEO PHARM PROD LTD (DK) 2003-07-16 CN claimed
CN-1422838-A Phenylbenzyl ketone purifying method SHANGHAI CHEMICAL REAGENT INST (CN) 2003-06-11 CN claimed
CN-1415984-A Method for preparing gradation type plastic optical fiber UNIV JIAOTONG (CN) 2003-05-07 CN claimed
CN-1415985-A Method for preparing prefabricated rod of gradation type plastic optical fiber UNIV JIAOTONG (CN) 2003-05-07 CN claimed
CN-1392147-A Aromatic cyclic polyketone oligomer and its preparing method CHANGCHUN APPLIED CHEMISTRY (CN) 2003-01-22 CN claimed
CN-1092178-C Methods for preparation of benzophenone derivatives HOFFMANN LA ROCHE (CH) 2002-10-09 CN claimed
CN-1359891-A Process for synthesizing miscible fluid of diphenyl ketone and p-phenylacetophenone ZHANG JIANGUO (CN) 2002-07-24 CN claimed
CN-1210512-A Method for hydroxylation of phenolic compounds RODIA CHIMIE S A (FR) 1999-03-10 CN claimed
CN-1134929-A Fungicidal methods, compounds and compositions contg. benzophenones AMERICAN CYANAMID CO (US) 1996-11-06 CN claimed
US-5284975-A Method of preparing α-d-phenylalkylbenzyl carbinol MALLINCKRODT SPECIALTY CHEMICALS COMPANY (US) 1994-02-08 US claimed