Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 9/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 4/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708196 | 0.88 | PPARD (0.47) | ALDH1A1LMNATARBP2PPARDPPARG | |
| SCHEMBL9833217 | 0.87 | HSD17B10 (0.44) | ALDH1A1LMNATARBP2PPARDPPARG | |
| Romazarit SCHEMBL43265 | 0.87 | ALDH1A1 (0.50) | ALDH1A1LMNATARBP2PPARDPPARG | |
| Romazarit SCHEMBL3226211 | 0.86 | ALDH1A1 (0.49) | ALDH1A1LMNATARBP2PPARDPPARG | |
| SCHEMBL9832600 | 0.81 | TARBP2 (0.51) | ALDH1A1LMNATARBP2PPARDPPARG | |
| SCHEMBL9831640 | 0.81 | ALDH1A1 (0.49) | ALDH1A1LMNATARBP2PPARDPPARG | |
| SCHEMBL9830393 | 0.80 | ALDH1A1 (0.54) | ALDH1A1LMNATARBP2PPARDPPARG | |
| Romazarit SCHEMBL9831287 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNATARBP2PPARDPPARG | |
| SCHEMBL9830056 | 0.78 | PPARA (0.50) | ALDH1A1LMNATARBP2PPARDPPARG | |
| SCHEMBL10746500 | 0.77 | TARBP2 (0.49) | ALDH1A1LMNATARBP2PPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4774253-A | ETHER,-ACIDS, ESTERS OR AMIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-09-27 | — | — | US | claimed |
| US-4774253-A | ETHER,-ACIDS, ESTERS OR AMIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-09-27 | — | — | US | disclosed |