Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832364 | 0.89 | HSD17B10 (0.43) | HSD17B10TARBP2ALDH1A1LMNAPPARA | |
| SCHEMBL9831297 | 0.88 | SLC16A3 (0.47) | HSD17B10TARBP2ALDH1A1LMNAPPARA | |
| SCHEMBL10712401 | 0.87 | ALDH1A1 (0.49) | HSD17B10TARBP2ALDH1A1LMNAPPARA | |
| SCHEMBL10708196 | 0.76 | PPARD (0.47) | HSD17B10TARBP2ALDH1A1LMNAPPARA | |
| SCHEMBL9834911 | 0.76 | HSD17B10 (0.48) | HSD17B10TARBP2ALDH1A1LMNAPPARA | |
| Romazarit SCHEMBL43265 | 0.74 | ALDH1A1 (0.50) | HSD17B10TARBP2ALDH1A1LMNAPPARA | |
| SCHEMBL12344817 | 0.73 | KDM4E (0.55) | HSD17B10TARBP2ALDH1A1LMNAPPARA | |
| Romazarit SCHEMBL3226211 | 0.73 | ALDH1A1 (0.49) | HSD17B10TARBP2ALDH1A1LMNAPPARA | |
| SCHEMBL9830013 | 0.71 | PPARA (0.57) | HSD17B10TARBP2PPARAPPARGPPARD | |
| SCHEMBL18003574 | 0.71 | ALDH1A1 (0.45) | HSD17B10TARBP2ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220573-B1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 1991-12-11 | — | — | EP | claimed |