Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CEL | P19835 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPRF | P10586 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19365988 | 0.79 | HTR2C (0.43) | HTR1AHTR7ADRA2AADRA2BADRA2C | |
| SCHEMBL11527808 | 0.76 | PTGDR2 (0.42) | HTR1AADRA2AADRA2BADRA2CPTGDR2 | |
| SCHEMBL654370 | 0.75 | PTGDR2 (0.42) | HTR1AHTR7ADRA2AADRA2BADRA2C | |
| SCHEMBL301130 | 0.74 | HTR1A (0.38) | HTR1AHTR7PTGS2CELPTGDR2 | |
| SCHEMBL260121 | 0.74 | HTR1A (0.38) | HTR1AHTR7PTGS2CELPTGDR2 | |
| SCHEMBL301162 | 0.74 | HTR1A (0.38) | HTR1AHTR7PTGS2CELPTGDR2 | |
| SCHEMBL15577021 | 0.74 | NOS3 (0.37) | HTR1AHTR7PTGS2SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL29208047 | 0.74 | PTGDR2 (0.41) | HTR1AHTR7ADRA2AADRA2BADRA2C | |
| SCHEMBL15286193 | 0.73 | PTGDR2 (0.40) | HTR1AHTR7ADRA2AADRA2BADRA2C | |
| SCHEMBL9634731 | 0.73 | HTR1A (0.37) | HTR1AHTR7PTGS2CELPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4668823-A | ARYLDICHLOROPHOSPHINE, TWO GRIGNARDS | UNION CARBIDE CORPORATION (US) | 1987-05-26 | — | — | US | disclosed |