Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 7/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15605734 | 0.90 | CA12 (0.34) | DNM1TSHRCA12CA1CA9 | |
| SCHEMBL15605738 | 0.86 | CA12 (0.32) | CA12CA1CA9 | |
| SCHEMBL20130845 | 0.72 | CA12 (0.36) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL15605733 | 0.70 | — | — | |
| SCHEMBL20130839 | 0.68 | CA12 (0.33) | CA12CA1CA9 | |
| SCHEMBL24728638 | 0.67 | DNM1 (0.50) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL16618697 | 0.67 | DNM1 (0.50) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL25286709 | 0.67 | DNM1 (0.50) | DNM1TSHRTHRBCA12CA1 | |
| Decane SCHEMBL3182487 | 0.66 | TSHR (0.73) | DNM1TSHRTHRBALDH1A1LMNA | |
| Hexadecane SCHEMBL27375271 | 0.66 | TSHR (0.73) | DNM1TSHRTHRBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069256-B1 | ONE PACKAGE, STABLE, MOISTURE CURABLE, POLYALKOXY-TERMINATED ORGANOPOLYSILOXANE COMPOSITIONS AND METHOD FOR MAKING | GENERAL ELECTRIC COMPANY (US) | 1988-09-07 | — | — | EP | claimed |
| US-4395526-A | SILANE SCAVENGER | GENERAL ELECTRIC COMPANY (US) | 1983-07-26 | — | — | US | claimed |
| WO-1983000156-A1 | ONE PACKAGE, STABLE, MOISTURE CURABLE, POLYALKOXY-TERMINATED ORGANOPOLYSILOXANE COMPOSITIONS AND METHOD FOR MAKING | GEN ELECTRIC (US) | 1983-01-20 | — | — | WO | claimed |
| EP-0069256-A2 | One package, stable, moisture curable, polyalkoxy-terminated organopolysiloxane compositions and method for making | GENERAL ELECTRIC COMPANY (US) | 1983-01-12 | — | — | EP | claimed |