Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11326003 | 0.80 | LMNA (0.46) | LMNA | |
| SCHEMBL11326509 | 0.75 | SMN1; SMN2 (0.42) | LMNA | |
| SCHEMBL11338543 | 0.70 | KCNH2 (0.41) | LMNA | |
| SCHEMBL10716427 | 0.69 | TRPM5 (0.41) | — | |
| SCHEMBL18901152 | 0.67 | — | — | |
| SCHEMBL11338555 | 0.66 | S1PR4 (0.40) | LMNA | |
| SCHEMBL11341711 | 0.66 | SMN1; SMN2 (0.40) | LMNA | |
| SCHEMBL12146358 | 0.66 | KMT2A (0.51) | LMNA | |
| SCHEMBL11324894 | 0.66 | LMNA (0.45) | LMNA | |
| SCHEMBL8388694 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4666502-A | Herbicidal N-thienyl-chloroacetamides | SANDOZ LTD. (CH) | 1987-05-19 | — | — | US | disclosed |