Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1622163 | 0.88 | ALDH1A1 (0.40) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL1621552 | 0.78 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL866857 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL28144774 | 0.75 | TSHR (0.40) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL20348617 | 0.73 | TSHR (0.44) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL1620942 | 0.71 | ALDH1A1 (0.36) | ALDH1A1TSHRTP53 | |
| SCHEMBL29250727 | 0.71 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL3777121 | 0.71 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL19312138 | 0.71 | TSHR (0.36) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL85493 | 0.70 | TSHR (0.57) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4645820-A | MOLDING MATERIAL FROM DIHYDRIC PHENOL, BIS(A,A-DISUBSTITUTED ACETIC ACID) SULFONE, AND 4,4*-BENZOPHENONE DICARBOXYLIC ACID | ATLANTIC RICHFIELD COMPANY (US) | 1987-02-24 | — | — | US | disclosed |
| EP-0210763-A1 | Moldable polyester-sulfone thermoplastic resin | ARCO CHEMICAL TECHNOLOGY, INC. (US) | 1987-02-04 | — | — | EP | disclosed |
| US-4614767-A | FROM DIHYDRIC PHENOL AND A BISCA,A-DISUBSTITUTED ACETIC ACID | ATLANTIC RICHFIELD COMPANY (US) | 1986-09-30 | — | — | US | disclosed |