SCHEMBL866857

SCHEMBL866857

CC(C)(C(=O)O)S(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TSHR P16473 3/20 0.42
ALOX15 P16050 1/20 0.37
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10714767 0.78 ALDH1A1 (0.44) ALDH1A1L3MBTL1TSHRALOX15CYP2D6
SCHEMBL27715552 0.75 ALDH1A1 (0.46) ALDH1A1L3MBTL1TSHRCYP2D6CYP2C19
SCHEMBL1621552 0.75 ALDH1A1 (0.42) ALDH1A1L3MBTL1TSHRALOX15CYP2D6
SCHEMBL1169404 0.75 ALDH1A1 (0.33) ALDH1A1L3MBTL1ALOX15
Pivalate SCHEMBL28392338 0.73 ALDH1A1 (0.47) ALDH1A1L3MBTL1TSHRALOX15CYP2D6
SCHEMBL1622163 0.73 ALDH1A1 (0.40) ALDH1A1L3MBTL1TSHRALOX15CYP2D6
SCHEMBL2373498 0.73 ALDH1A1 (0.47) ALDH1A1L3MBTL1TSHRCYP2D6CYP2C19
SCHEMBL28144774 0.73 TSHR (0.40) ALDH1A1L3MBTL1TSHRALOX15CYP2D6
SCHEMBL6632023 0.73 ALDH1A1 (0.43) ALDH1A1L3MBTL1TSHRCYP2D6CYP2C19
SCHEMBL3989015 0.73 BLM (0.32) ALDH1A1L3MBTL1TSHRALOX15CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2622016-B1 ENERGY RECOVERY VENTILATION SULFONATED BLOCK COPOLYMER LAMINATE MEMBRANE KRATON POLYMERS US LLC (US) 2023-06-07 EP disclosed
CN-108884055-B Pyridazinone compound or salt thereof, and herbicide containing same 石原产业株式会社 2022-07-12 CN disclosed
US-11021559-B2 Sulfonated block copolymer laminates with polar or active metal substrates KRATON POLYMERS LLC (US) 2021-06-01 US disclosed
US-20210010759-A1 ENHANCED-EFFICIENCY ENERGY RECOVERY VENTILATION CORE KRATON POLYMERS LLC (US) 2021-01-14 US disclosed
CN-112137995-A Methods and mixtures for increasing the cellular availability of calcium in skin cells 默克专利股份有限公司 2020-12-29 CN disclosed
US-20200071447-A1 Sulfonated Block Copolymer Laminates with Polar or Active Metal Substrates KRATON POLYMERS LLC (US) 2020-03-05 US disclosed
CN-110730820-A Aldehyde dehydrogenase variants and methods of use 基因组股份公司 2020-01-24 CN disclosed
CN-110691847-A 3-hydroxybutyryl-CoA dehydrogenase variants and methods of use 基因组股份公司 2020-01-14 CN disclosed
EP-2893281-B1 ENHANCED-EFFICIENCY ENERGY RECOVERY VENTILATION CORE KRATON POLYMERS US LLC (US) 2019-10-02 EP disclosed
EP-2943514-B1 ANION EXCHANGE BLOCK COPOLYMERS, THEIR MANUFACTURE AND THEIR USE KRATON POLYMERS US LLC (US) 2019-06-05 EP disclosed
WO-2009089541-A2 A NEW INHIBITOR SCAFFOLD FOR THE INHIBITION OF THE ENZYME PHOSPHOENOLPYRUVATE CARBOXYKINASE UNIVERSITY OF KANSAS (US) 2009-07-16 WO disclosed
US-7517875-B2 Piperidine derivatives having CCR3 antagonism TEIJIN LIMITED (JP) 2009-04-14 US disclosed
WO-2008089332-A2 METHOD OF SULFONATION OF BLOCK POLYMERS STEPAN COMPANY (US) 2008-07-24 WO disclosed
US-20070032525-A1 Piperidine derivatives having ccr3 antagonism TEIJIN LIMITED, A JAPANESE BODY CORPORATE (JP) 2007-02-08 US disclosed
EP-1502916-A1 PIPERIDINE DERIVATIVES HAVING CCR3 ANTAGONISM TEIJIN LIMITED (JP) 2005-02-02 EP disclosed
US-6583250-B2 Particularly to cyanoacrylate adhesives, by mixing in a polymerization initiator capable of initiating polymerization of the monomers of the adhesive, at a temperature above the polyolefin's glass transition temperature HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-06-24 US disclosed
CN-1096448-C Farnesyl transferase inhibitors, its preparation and medicine composition thereof RHONE POULENC RORER SA (FR) 2002-12-18 CN disclosed
US-20010009954-A1 POLYOLEFINE MATERIALS WITH IMPROVED ADHESIVITY COGNIS DEUTSCHLAND GMBH & CO. KG (DE) 2001-07-26 US disclosed
CN-1190389-A Novel farnesyl transferase inhibitors, process for their preparation and pharmaceutical compositions containing them RHONE POULENC RORER SA (FR) 1998-08-12 CN disclosed
US-4601904-A Antibiotics xylocandin A and xylocandin B E. R. SQUIBB & SONS, INC. (US) 1986-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032525-A1 Piperidine derivatives having ccr3 antagonism CCR3, CCR1, CCR4 ALDH1A1 451/4885L3MBTL1 3446/4885TSHR 3393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.