SCHEMBL10715137

SCHEMBL10715137

NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 5/20 0.58
▸ SLC7A5 Q01650 1/20 0.57
▸ ACE P12821 6/20 0.56
▸ CPA1 P15085 1/20 0.56
▸ ACE2 Q9BYF1 1/20 0.56
▸ FOLH1 Q04609 1/20 0.55
▸ NAALAD2 Q9Y3Q0 1/20 0.55
▸ CA1 P00915 1/20 0.52
▸ CA2 P00918 1/20 0.52
▸ YARS1 P54577 2/20 0.51
▸ NPY1R P25929 1/20 0.51
▸ NPY2R P49146 1/20 0.51
▸ NPY4R P50391 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2228574 1.00 MME (0.58) MMESLC7A5ACECPA1ACE2
SCHEMBL30122989 0.96 MME (0.54) MMESLC7A5ACECPA1ACE2
SCHEMBL29630361 0.96 MME (0.54) MMESLC7A5ACECPA1ACE2
SCHEMBL30839491 0.95 MME (0.53) MMESLC7A5ACECPA1ACE2
SCHEMBL30123104 0.93 ENPEP (0.56) MMESLC7A5ACECPA1ACE2
SCHEMBL29619568 0.93 ENPEP (0.56) MMESLC7A5ACECPA1ACE2
SCHEMBL29430160 0.92 ENPEP (0.55) MMESLC7A5ACECPA1ACE2
SCHEMBL1574161 0.91 SLC7A5 (0.65) MMESLC7A5ACECPA1ACE2
SCHEMBL1574158 0.91 SLC7A5 (0.65) MMESLC7A5ACECPA1ACE2
SCHEMBL31025673 0.91 SLC7A5 (0.65) MMESLC7A5ACECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12050228-B2 Automated sample quality assessment METABOLON, INC. (US) 2024-07-30 — — US claimed
US-11382911-B2 Plant extract containing diketopiperazine and method for producing same SUNTORY HOLDINGS LIMITED (JP) 2022-07-12 — — US claimed
US-20210088539-A1 AUTOMATED SAMPLE QUALITY ASSESSMENT METABOLON, INC. 2021-03-25 — — US claimed
US-10890592-B2 Automated sample quality assessment METABOLON, INC. (US) 2021-01-12 — — US claimed
WO-2020071258-A1 PROTEIN GLYCATION SUPPRESSANT 味の素株式会社 2020-04-09 — — WO claimed
EP-3967217-B1 BLOOD BASED BIOMARKERS FOR DIAGNOSING ATHEROSCLEROTIC CORONARY ARTERY DISEASE GLOBAL GENOMICS GROUP LLC (US) 2024-08-14 — — EP disclosed
US-20240257973-A1 DISEASE SPECTRUM CLASSIFICATION PATIENTSLIKEME LLC (US) 2024-08-01 — — US disclosed
US-12050228-B2 Automated sample quality assessment METABOLON, INC. (US) 2024-07-30 — — US disclosed
US-11894139-B1 Disease spectrum classification PATIENTSLIKEME LLC (US) 2024-02-06 — — US disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 — — US disclosed
US-11382911-B2 Plant extract containing diketopiperazine and method for producing same SUNTORY HOLDINGS LIMITED (JP) 2022-07-12 — — US disclosed
EP-3967217-A1 BLOOD BASED BIOMARKERS FOR DIAGNOSING ATHEROSCLEROTIC CORONARY ARTERY DISEASE Global Genomics Group, LLC (US) 2022-03-16 — — EP disclosed
WO-2015017866-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. (US) 2015-02-05 — — WO disclosed
EP-0109418-A4 GONADOLIBERIN DERIVATIVES, PROCESS FOR THE PREPARATION AND PHARMACEUTICAL AND VETERINARY COMPOSITIONS THEREOF. RICHTER GEDEON VEGYESZET (HU) 1987-11-12 — — EP disclosed
US-4691008-A COUPLING A URETHANE-BLOCKED TRIPEPTIDE AND A PEPTIDE WITH A FREE AMINE USING A CONDENSATION AGENT HOECHST AKTIENGESELLSCHAFT (DE) 1987-09-01 — — US disclosed
US-4552864-A Gonadoliberin derivatives process for the preparation and pharmaceutical compositions thereof REANAL FINOMVEGYSZERGYAR (HU) 1985-11-12 — — US disclosed
EP-0109418-A1 GONADOLIBERIN DERIVATIVES, PROCESS FOR THE PREPARATION AND PHARMACEUTICAL AND VETERINARY COMPOSITIONS THEREOF REANAL FINOMVEGYSZERGYAR (HU) 1984-05-30 — — EP disclosed
WO-1983004250-A1 GONADOLIBERIN DERIVATIVES, PROCESS FOR THE PREPARATION AND PHARMACEUTICAL AND VETERINARY COMPOSITIONS THEREOF RICHTER GEDEON VEGYÉSZETI GYÁR R.T. (HU) 1983-12-08 — — WO disclosed
US-4242256-A Synthesis of peptide analogues SHARPE ROBERT (GB) 1980-12-30 — — US disclosed
US-3963691-A POLYPEPTIDES, PEPTIZATION MERCK & CO., INC. (US) 1976-06-15 — — US disclosed
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