SCHEMBL2228574

SCHEMBL2228574

N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 5/20 0.58
▸ SLC7A5 Q01650 1/20 0.57
▸ ACE P12821 6/20 0.56
▸ CPA1 P15085 1/20 0.56
▸ ACE2 Q9BYF1 1/20 0.56
▸ FOLH1 Q04609 1/20 0.55
▸ NAALAD2 Q9Y3Q0 1/20 0.55
▸ CA1 P00915 1/20 0.52
▸ CA2 P00918 1/20 0.52
▸ YARS1 P54577 2/20 0.51
▸ NPY1R P25929 1/20 0.51
▸ NPY2R P49146 1/20 0.51
▸ NPY4R P50391 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10715137 1.00 MME (0.58) MMESLC7A5ACECPA1ACE2
SCHEMBL30122989 0.96 MME (0.54) MMESLC7A5ACECPA1ACE2
SCHEMBL29630361 0.96 MME (0.54) MMESLC7A5ACECPA1ACE2
SCHEMBL30839491 0.95 MME (0.53) MMESLC7A5ACECPA1ACE2
SCHEMBL30123104 0.93 ENPEP (0.56) MMESLC7A5ACECPA1ACE2
SCHEMBL29619568 0.93 ENPEP (0.56) MMESLC7A5ACECPA1ACE2
SCHEMBL29430160 0.92 ENPEP (0.55) MMESLC7A5ACECPA1ACE2
SCHEMBL1574161 0.91 SLC7A5 (0.65) MMESLC7A5ACECPA1ACE2
SCHEMBL1574158 0.91 SLC7A5 (0.65) MMESLC7A5ACECPA1ACE2
SCHEMBL31025673 0.91 SLC7A5 (0.65) MMESLC7A5ACECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695413-A1 PHOSPHONOALANINE OLIGOPEPTIDES AND METHODS OF MAKING AND USE THEREOF Ohio State Innovation Foundation (US) 2026-02-18 — — EP claimed
US-12377110-B2 Fospropofol methods and compositions EPALEX CORPORATION (US) 2025-08-05 — — US claimed
CN-120195298-A Metabolic marker composition for discriminating tobacco grades, screening method and application 哈尔滨脉图精准技术有限公司 2025-06-24 — — CN claimed
WO-2024216031-A1 PHOSPHONOALANINE OLIGOPEPTIDES AND METHODS OF MAKING AND USE THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2024-10-17 — — WO claimed
US-12050228-B2 Automated sample quality assessment METABOLON, INC. (US) 2024-07-30 — — US claimed
CN-117586347-A A hirudin with antidiabetic activity and its application 滨州医学院 2024-02-23 — — CN claimed
US-20230084521-A1 PROPOFOL PRODRUG METHODS AND COMPOSITIONS EPALEX CORPORATION 2023-03-16 — — US claimed
US-11382911-B2 Plant extract containing diketopiperazine and method for producing same SUNTORY HOLDINGS LIMITED (JP) 2022-07-12 — — US claimed
US-20220105050-A1 PROPOFOL PRODRUG METHODS AND COMPOSITIONS EPALEX CORPORATION 2022-04-07 — — US claimed
US-20210088539-A1 AUTOMATED SAMPLE QUALITY ASSESSMENT METABOLON, INC. 2021-03-25 — — US claimed
US-10890592-B2 Automated sample quality assessment METABOLON, INC. (US) 2021-01-12 — — US claimed
WO-2020071258-A1 PROTEIN GLYCATION SUPPRESSANT 味の素株式会社 2020-04-09 — — WO claimed
US-20020147317-A1 Fluorogenic compounds and uses therefor 3M INNOVATIVE PROPETIES COMPANY 2002-10-10 — — US claimed
US-6372895-B1 USEFUL IN ASSAYING FOR BIOLOGICAL ACTIVITY 3M INNOVATIVE PROPERTIES COMPANY 2002-04-16 — — US claimed
EP-0122151-B1 PRODUCTION OF PRIMARY OR SECONDARY ALCOHOL DERIVATIVES OF PHOSPHOLIPIDS BY THE ENZYMATIC TECHNIQUE MEITO SANGYO KABUSHIKI KAISHA (JP) 1989-02-15 — — EP claimed
US-4783402-A Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique MEITO SANGYO KABUSHIKI KAISHA (JP) 1988-11-08 — — US claimed
EP-0122151-A2 Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique MEITO SANGYO KABUSHIKI KAISHA (JP) 1984-10-17 — — EP claimed
WO-2026089752-A1 COMPOSITIONS AND METHODS FOR MICROSPHERE DELIVERY OF THERAPEUTIC PEPTIDES Finitus, LLC (US) 2026-04-30 — — WO disclosed
US-4242256-A Synthesis of peptide analogues SHARPE ROBERT (GB) 1980-12-30 — — US disclosed
US-3963691-A POLYPEPTIDES, PEPTIZATION MERCK & CO., INC. (US) 1976-06-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020147317-A1 Fluorogenic compounds and uses therefor NOTUM, WEE1, CPSF7 MME 815/4885SLC7A5 2103/4885ACE 2808/4885
US-12377110-B2 Fospropofol methods and compositions FOS, FOSB, PFAS MME 2240/4885SLC7A5 2919/4885ACE 573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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