Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL90706 | 0.81 | EPHX1 (0.46) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL24298159 | 0.81 | EPHX1 (0.46) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL89503 | 0.81 | EPHX1 (0.46) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL9646158 | 0.80 | CTSK (0.42) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL3122584 | 0.80 | EPHX1 (0.48) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL1414447 | 0.80 | EPHX1 (0.48) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL2702388 | 0.80 | EPHX1 (0.48) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL12733104 | 0.80 | EPHX1 (0.48) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL9646336 | 0.80 | CTSS (0.37) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL8282037 | 0.79 | EPHX1 (0.47) | HDAC4HDAC1HDAC6EPHX1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | disclosed |