Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPEP1 | P16444 | 10/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7283296 | 0.99 | DPEP1 (0.48) | DPEP1METAP1CTSKANPEPERAP2 | |
| SCHEMBL7277423 | 0.75 | ANPEP (0.47) | DPEP1METAP1ANPEPERAP2MMP1 | |
| SCHEMBL10439822 | 0.74 | DPEP1 (0.50) | DPEP1METAP1 | |
| SCHEMBL9646445 | 0.74 | DPEP1 (0.50) | DPEP1METAP1 | |
| Bromide SCHEMBL10716158 | 0.74 | ANPEP (0.46) | DPEP1METAP1ANPEPERAP2MMP1 | |
| SCHEMBL9647128 | 0.72 | DPEP1 (0.63) | DPEP1METAP1 | |
| SCHEMBL9647109 | 0.72 | DPEP1 (0.63) | DPEP1METAP1 | |
| SCHEMBL9645166 | 0.72 | DPEP1 (0.63) | DPEP1METAP1 | |
| SCHEMBL9646942 | 0.72 | DPEP1 (0.63) | DPEP1METAP1 | |
| SCHEMBL9647139 | 0.72 | DPEP1 (0.63) | DPEP1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | claimed |
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | disclosed |