Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2521080 | 0.87 | ALDH1A1 (0.34) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL16433325 | 0.81 | TSHR (0.35) | TSHRLMNAALDH1A1TP53HIF1A | |
| SCHEMBL17792467 | 0.81 | TSHR (0.35) | TSHRLMNAALDH1A1TP53HIF1A | |
| Hydrogen Peroxide SCHEMBL27482921 | 0.80 | LMNA (0.38) | TSHRLMNAALDH1A1TP53HIF1A | |
| SCHEMBL9862196 | 0.80 | TSHR (0.33) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL28189986 | 0.79 | TSHR (0.34) | TSHRLMNAALDH1A1TP53HIF1A | |
| SCHEMBL28082667 | 0.79 | TSHR (0.38) | TSHRLMNAALDH1A1TP53HIF1A | |
| SCHEMBL31091781 | 0.79 | TSHR (0.34) | TSHRLMNAALDH1A1TP53HIF1A | |
| SCHEMBL429636 | 0.77 | TSHR (0.33) | TSHRLMNAALDH1A1TP53HIF1A | |
| SCHEMBL22442055 | 0.77 | TSHR (0.33) | TSHRLMNAALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161773-B1 | SURFACTANT SYSTEM FOR EMULSION POLYMERS | CALGON CORPORATION (US) | 1988-11-09 | — | — | EP | claimed |