SCHEMBL10716861

SCHEMBL10716861

CC(=C(C(=O)O)C(=O)O)c1nccs1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
RBBP9 O75884 5/20 0.44
PLA2G4A P47712 1/20 0.40
CYP1A2 P05177 3/20 0.39
CYP2D6 P10635 3/20 0.39
CYP2C19 P33261 3/20 0.39
CASP3 P42574 3/20 0.39
SENP8 Q96LD8 3/20 0.39
SENP7 Q9BQF6 3/20 0.39
SENP6 Q9GZR1 3/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
CES1 P23141 1/20 0.39
KMT2A Q03164 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PLA2G7 Q13093 1/20 0.37
HSPA9 P38646 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL247631 0.77
SCHEMBL11254334 0.75 ALDH1A1 (0.59) ALDH1A1RBBP9PLA2G4ACYP1A2CYP2D6
Bromide SCHEMBL27358834 0.75
SCHEMBL8213363 0.74
SCHEMBL121301 0.74
SCHEMBL5609136 0.74 ALDH1A1 (0.69) ALDH1A1RBBP9PLA2G4ACYP1A2CYP2D6
SCHEMBL15122549 0.73 ALDH1A1 (0.57) ALDH1A1RBBP9PLA2G4ACYP1A2CYP2D6
SCHEMBL10505199 0.73 ALDH1A1 (0.47) ALDH1A1RBBP9PLA2G4ACASP3SENP8
Hydrochloric Acid SCHEMBL1128589 0.73
SCHEMBL5484928 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4652652-A PENICILLIN OR CEPHALOSPORIN INTERMEDIATE SHIONOGI & CO., LTD. (JP) 1987-03-24 US disclosed