Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | RBBP9 | O75884 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027936 | 0.74 | — | — | |
| SCHEMBL247631 | 0.73 | — | — | |
| SCHEMBL1768160 | 0.71 | — | — | |
| Bromide SCHEMBL27358834 | 0.71 | — | — | |
| SCHEMBL28219561 | 0.69 | ALDH1A1 (0.68) | ALDH1A1RBBP9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL746203 | 0.69 | — | — | |
| SCHEMBL21706524 | 0.69 | — | — | |
| SCHEMBL3037364 | 0.68 | — | — | |
| SCHEMBL28803621 | 0.68 | ALDH1A1 (0.50) | ALDH1A1RBBP9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL175249 | 0.68 | ALDH1A1 (0.67) | ALDH1A1RBBP9CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150299196-A1 | Flindersia Alkaloids, Derivatives and Analogs: Compositions and Methods for Producing the Same | UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-10-22 | — | — | US | claimed |
| US-9067946-B2 | Flindersia alkaloids, derivatives and analogs: compositions and methods for producing the same | UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-06-30 | — | — | US | claimed |
| WO-2013109866-A1 | FLINDERSIA ALKALOIDS, DERIVATIVES AND ANALOGS: COMPOSITIONS AND METHODS FOR PRODUCING THE SAME | UNIVERSITY OF HOUSTON SYSTEM (US) | 2013-07-25 | — | — | WO | claimed |
| US-20130190511-A1 | Flindersia Alkaloids, Derivatives and Analogs: Compositions and Methods for Producing the Same | HOUSTON SYSTEM, UNIVERSITY OF | 2013-07-25 | — | — | US | claimed |
| US-9353109-B2 | Flindersia alkaloids, derivatives and analogs: compositions and methods for producing the same | UNIVERSITY OF HOUSTON SYSTEM (US) | 2016-05-31 | — | — | US | disclosed |
| US-20150299196-A1 | Flindersia Alkaloids, Derivatives and Analogs: Compositions and Methods for Producing the Same | UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-10-22 | — | — | US | disclosed |
| US-9067946-B2 | Flindersia alkaloids, derivatives and analogs: compositions and methods for producing the same | UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-06-30 | — | — | US | disclosed |
| WO-2013109866-A1 | FLINDERSIA ALKALOIDS, DERIVATIVES AND ANALOGS: COMPOSITIONS AND METHODS FOR PRODUCING THE SAME | UNIVERSITY OF HOUSTON SYSTEM (US) | 2013-07-25 | — | — | WO | disclosed |
| US-20130190511-A1 | Flindersia Alkaloids, Derivatives and Analogs: Compositions and Methods for Producing the Same | HOUSTON SYSTEM, UNIVERSITY OF | 2013-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190511-A1 | Flindersia Alkaloids, Derivatives and Analogs: Compositions and Methods for Producing the Same | NAAA, MAOA, AANAT | ALDH1A1 2072/4885RBBP9 2416/4885CYP1A2 1558/4885 |
| US-20150299196-A1 | Flindersia Alkaloids, Derivatives and Analogs: Compositions and Methods for Producing the Same | MAOA, NAAA, FLNA | ALDH1A1 2383/4885RBBP9 2445/4885CYP1A2 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.